Do you know how long you have had lyme?
When I first started treatment (after 5 years undiagnosed) I got so much worse. I didn't think I could get any worse, but I did. I thought it would last a few months and I would get better, but I was sick for a long time with no improvement. I would say almost a year before I saw even the smallest sign that I was getting better. Then during my second year of treatment I noticed I was getting better. I stayed on another 6 months to make sure I was well when I stopped abx so overall I was on for 2 1/2 years.
The saying goes, you have to get a lot worse before you get better. I just had to have faith that the meds were working and so I stayed on them.