Unfortunately, I do know for sure that my EDS was inherited and my specialist said 70% of EDS patients get POTS on some level. My great aunt, Mom, and sister have EDS and my sister had POTS as a teen. Unless some infectious disease was passed down from my great grandmother to all of us? She didn't have EDS by the way and lived in her own home until 93. :)
I've accepted the EDS is here to stay, but I think if I could figure out this infection clearly going on with my lymph nodes, I could get the POTS under control.
Whenever I try to up the activity level to help with the POTS (or my sanity), I get a fever and my lymph nodes swell up. Sometimes I ignore it, but it just compounds and after a week or so of "overdoing it", I won't be able to move my arms because the armpit lymph nodes cause so much pain. If I just do bed rest and don't do things like get on the computer too long or talk too much, they stay down until late evening, but that is just no way to live life!