Thank you to everyone who have taken the time to respond. Your advice and support is greatly appreciated.
It turns out that some of you were correct and that indeed my progress is being hindered by a co-infection - Bartonella!
I'm now being treated for that and my treatment regimen has now completely changed
Lyme treatment has been upped to become more aggressive and Bartonella medication added in - Rifampin 600mg per day with Biaxin.
Since starting I've had my first proper herx and now believe that my major problem is Bartonella and perhaps not Lyme!
Needless to say the fight goes on...!
37 yr old female
Tick bite July 2013; followed by EM rash
August 2013 - symptoms begin
Igenix WB positive for Lyme - Feb 2014
Infectolab (Germany) positive for Lyme - Feb 2014
Clinical diagnosis of Bartonella
Start of treatment at end of Feb 2014 - 4 weeks of IV Ceftraxione
Current treatment - Clarithromycin, Amoxicillin, Rifampin