Anyone feel worse after glutathione?

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pictureofhealth
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Date Joined Dec 2013
Total Posts : 482
   Posted 8/13/2014 7:17 PM (GMT -7)   
After my IV abx on monday and today I got dose of glutathione. Both times I felt horrible, shaky and out of it for a couple of hours. I was just wondering if anyone else has had a bad reaction to it? I was so hoping this was going to be the magic potion. Everything I read about it says it's a wonder drug. Any ideas on why I would react this way?

Delmar
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Date Joined Apr 2014
Total Posts : 522
   Posted 8/14/2014 8:02 AM (GMT -7)   
Yep!
Not the orals, that I've noticed, but the IVs cause me to herx (at least I believe it's a herx), usually lasts a day or two and I feel extremely tired and usually very emotional. Then I usually feel much better by the 2nd or 3rd day. My integrative doctor told me that these could definitely cause a herx because its boosting the immune system and removing toxins.
Symptoms began October 2013
15 doctors from Feb. - April 2014
Began treatment with LLMD & tested Igenex + 4/2014

Zithro 600 mg x2/daily, Ceftin 500 mg x2/daily, IV/oral glutathione & PC, multiV, magnesium, calcium/D, probiotic, vit c, YL essential oils (thieves, lemon, panaway, oregano, Lyme Bullets, rain drops x1/wk, inner d), L-lysine, milk thistle, cats claw, red root, detoxing and exercise

Akkami
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Date Joined Nov 2013
Total Posts : 329
   Posted 8/14/2014 9:35 AM (GMT -7)   
Yes. I feel bad for a few hours usually. Very tired and weak. Only the IV though. Orals don't seem to do that to me.

opugirl
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Date Joined Nov 2012
Total Posts : 3577
   Posted 8/14/2014 11:10 AM (GMT -7)   
Hi pictureofhealth,

I have heard of this and if you search on the internet quite a bit comes up in regards to herxing from glutathione. That may just mean that your body has a hard time detoxing, or your body is depleted in glutathione (making it harder to detox) and then when you get it, it is somewhat overwhelming. Not necessarily a bad thing - it is probably working then and getting toxins out.

I would just keep track of how you feel with it and hopefully - the more you continue with the IV's, the less intense the feelings might be. Drink lots and lots of water after you do an IV (I know you probably already are smilewinkgrin )

Do you just feel a bit off for a few hours?

~beth
Forum Moderator

July 2007 - Deer tick bite w/ physician confirmed EM Rash - given 10 days of Doxy
October 2012 - My world gets rocked January 2013 - My world turns upside down
March 2013 - Igenex +, start treatment with LLMD, LLND, and herbalist
August 2013- Finished all abx, continuing with herbs and homeopathy, Feeling good!
July 2014- Off all treatment since Jan 2014, just taking vitamins

Delmar
Veteran Member


Date Joined Apr 2014
Total Posts : 522
   Posted 8/14/2014 12:00 PM (GMT -7)   
I feel tired and very emotional for the entire day, the day I have it done. But my doctor said its a herx
Symptoms began October 2013
15 doctors from Feb. - April 2014
Began treatment with LLMD & tested Igenex + 4/2014

Zithro 600 mg x2/daily, Ceftin 500 mg x2/daily, IV/oral glutathione & PC, multiV, magnesium, calcium/D, probiotic, vit c, YL essential oils (thieves, lemon, panaway, oregano, Lyme Bullets, rain drops x1/wk, inner d), L-lysine, milk thistle, cats claw, red root, detoxing and exercise

Jam79
New Member


Date Joined Jan 2015
Total Posts : 1
   Posted 1/15/2015 11:21 AM (GMT -7)   
I started IV Glutathione at an extremely low dose and got very sick for about three days with exhaustion, low mood, and generally feeling weak and ill. I researched it a bit and spoke with my doctor and it seems that for people who have, a) very low glutathione to begin with from chronic illness or a genetic inability to produce enough, and/or b) have a very toxic system will herx from Glutathione. Basically what I discovered is the more you react, the better the effect - it means your liver was backed up and your immune system was down. The glutathione is clearing things out and helping to rev up your own Immunity. We reduced the amount for the next visit and I was able to tolerate more gradually, and without any problem.

If you are on any medications, keep in mind that the glutathione may push them through the system faster, especially that day. I am on SSRI's and I noticed a change in my mood and a headache when I started so I took my pill after my glutathione so that it wouldn't get washed out so quickly.

SLML
Regular Member


Date Joined Jul 2012
Total Posts : 293
   Posted 1/15/2015 11:34 AM (GMT -7)   
Yes! My doctor had me take liposomal glutathione (smells like rotten eggs!) by Researched Nutritionals. I tried it two different times (2 different years) and I could only handle one dose of it. Nothing has made me feel instantly very angry and irritable like that stuff. It was almost like a major personality change within 30 minutes of taking it. I have had it mixed in a Meyer's Cocktail IV by my doctor before and didn't have the same reaction but I did fill nauseous. I wonder if it has something to do with being sulfer based. I don't have any sulfer gene mutations that I know of. It is one supplement that I have avoided because of that reason. Who knows, it has been a few years, with a lot of detoxing and treatment so I may not react the same now?

ela9050
Regular Member


Date Joined Jun 2014
Total Posts : 106
   Posted 1/15/2015 8:26 PM (GMT -7)   
Test with 23&me. Certain gene mutations do not like metholation aids. You might have the COMET mutation, if I remember correctly.

dying2getwell
Regular Member


Date Joined Nov 2014
Total Posts : 312
   Posted 1/17/2015 6:25 PM (GMT -7)   
I thought glutathione helps you remove toxins....and a herx, is when the toxins are being released from the microbes when being killed off, faster than your body can deal with it.
I don't understand how this can be a herx? Do you?

Do any of you feel like your doctor is making stuff up?

I did do some research, cuz I did have back pain, shortness of breath,whoozyness, chills, and fatigue after getting some IV glutathione. (yet, my jerking came to a stop, for some time).

Anyway, I think your body also has to metabolize it, brake it down...I need to do more research before I get my next dose. 2 doctors did tell me that some people have a hard time with it....while the one who gave it to me, said he never heard of such a thing....Something is happening inside, and I want to understand it.
Before getting another dose, I really need to do more research. I'm going to try to take it with molybdenom next time...and see if that does anything. It might help with metabolism, but I'm not sure.

I wonder if your doctor knows its a herx, and how that is possible. Or, if they make stuff up. I'm really curious about this, cuz I have the same problem.

pictureofhealth
Regular Member


Date Joined Dec 2013
Total Posts : 482
   Posted 1/17/2015 8:12 PM (GMT -7)   
I had a LLND appt. yesterday and she said to get the 23 and me test to find out what my methylation pathways are.
So thanks ela9050 it sounds like you are right!

KatieB
New Member


Date Joined Jun 2016
Total Posts : 16
   Posted 8/11/2016 11:24 AM (GMT -7)   
hi guys. I have the same issues w glutathione.....IV makes me feel dizzy, headache, woozy, and just generally crappy. oral has a weaker yet similar effect. I've tried it three times in all and not noticed any significant reduction in symptoms. awaiting 23 & me results. i wonder too if i have either a toxic system or just can't process sulphur well (though i eat eggs and other foods containing sulphur no problem)

anyone have updates to their symptoms? pictureofhealth....how do you tolerate glut these days? or did you stop taking it?

Traveler
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Date Joined May 2007
Total Posts : 35859
   Posted 8/11/2016 11:50 AM (GMT -7)   
Generally speaking, oral glutathione is not the best for a Lyme patient, as very little makes it past the stomach acid. Liposomal or IV are the best options. This doesn't mean you won't get any benefit from taking it orally, only that it will be limited.

Glutathione is the master antioxidant produced in the liver, so when it's taken, it will help move toxins and we have to be sure that the rest of our detoxing pathways are in good working order (by using many different 'manual' detoxing methods like dry skin brushing and others) in order to not experience an overload of toxins.
Herb only treatment for Lyme & Bart ended 12/11 - no active symptoms for 2 yrs -Herb only treatment for Babesia ended 12/12
www.healingwell.com/community/default.aspx?f=30&m=2977364
Had Lyme, Bart, Babs, RMSF, Ehrlichia, Myco, Anaplasmosis, EBV
New Lyme case 8/2014 - Healed 1/31/15 - unknowingly had Asymptomatic Babs and Asymptomatic Bart, being treated now though (2/2016)

Krimpet 🍔
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Date Joined Apr 2016
Total Posts : 3274
   Posted 8/11/2016 12:42 PM (GMT -7)   
KatieB said...
hi guys. I have the same issues w glutathione.....IV makes me feel dizzy, headache, woozy, and just generally crappy. oral has a weaker yet similar effect. I've tried it three times in all and not noticed any significant reduction in symptoms. awaiting 23 & me results. i wonder too if i have either a toxic system or just can't process sulphur well (though i eat eggs and other foods containing sulphur no problem)

anyone have updates to their symptoms? pictureofhealth....how do you tolerate glut these days? or did you stop taking it?


How quickly are they pushing the glutathione? If it's given too quickly, you can indeed have those symptoms. When I was getting it, it was veryyyyyyy slowwwwwww push.

Pirouette
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Date Joined Mar 2014
Total Posts : 6201
   Posted 8/11/2016 1:01 PM (GMT -7)   
I'm gearing up for my first glutathione IV and it's gonna be looooowwwww dose and veerrryyyyy sloooowwwwww and easy.

-p
Lyme Moderator
Chronic late-stage lyme—likely infected in 2000; Clinically dx Mar'14 w/ Babs, + for Bart, CDC + for Bb. Multiple viruses & GI/immune treated first; started AL-Complex in May, A-Bart & A-Bab in July; Nov'14 IV port installed-started Rocephin; added vancomycin Mar'16
DETOX: Pinella/Burbur/Parsley/Milk thistle/Burdock root; cholestyramine / jap. knotweed L-5-MTHFR LMN-V-II probiotic

Krimpet 🍔
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Date Joined Apr 2016
Total Posts : 3274
   Posted 8/11/2016 1:06 PM (GMT -7)   
Oh goody P. Let us know how it goes.
Lyme Moderator

August words of encouragement:
"F-E-A-R has two meanings:"
'Forget Everything and Run' or
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The choice is yours.

bluelyme
Veteran Member


Date Joined Nov 2015
Total Posts : 4441
   Posted 8/11/2016 4:14 PM (GMT -7)   
Go piro ..may help with detox ..as long as you dont have sulferation block it should be cool.. i push 1000 mg in 3 min 2 x a week ..can make you lil amped it is a vasodilator too...doc said melitonin high dose was as good or better antioxidant

KatieB
New Member


Date Joined Jun 2016
Total Posts : 16
   Posted 8/11/2016 7:22 PM (GMT -7)   
what is a sulphuration block and how do you know if you have it? i've been hearing a lot about people who can't tolerate sulphur have big problems with glutathione. any advice helpful or how to test for this.

bluelyme
Veteran Member


Date Joined Nov 2015
Total Posts : 4441
   Posted 8/11/2016 10:19 PM (GMT -7)   
Its a cbs genitic mutation. .like the mthfr detox thang ...so you get a 23 n me test and run it through a site like mthfr or genitic genie and it tell you your snps .how well geneitcally you can hang or in my case like a person with out arms- cant hang..i believe ther are some post if you cross genitic testing ..

1000Daisies
Veteran Member


Date Joined Apr 2016
Total Posts : 2059
   Posted 8/13/2016 4:46 PM (GMT -7)   
For Kid#1, he never had a physical herx in all of the initial, several years of treatment. Once we started IV Myers and Glutathione last year, he started having physical herxs like clockwork. It was very obvious, to me, it was related to the IVs. The physical herxs were chills, weak, and just feeling really miserable (kind of like a body flu virus). For me, it was like it "woke up his immune system".

Now, he doesn't seem to have them anymore. At least, he hasn't had them in months. He had responded really positively to pinellla/burbur at the first sign of a physical herx. Before, he would miss school, but the first time I tried the pinella/burbur, he was back at school within a few hours. It was pretty remarkable.
I don't know what it means now that he's not herxing. Has he gone back to a sleeping immune system (I don't know if it really was sleeping but that's what it seems like to me) or has he finally healed enough to not be herxing like clockwork? I honestly don't know.

Kid#2 and Kid#3 did not react to the IVs. Except - Kid#2 had to urinate an insane amount of time within the first couple hours after his first IVs. I don't recall any good (or bad) from those IVs for those two kids.
Kid#1: Extremely sick for several years, very difficult to treat, improved now but not fully well
Kid#2: Very sick now despite being treated for years
Kid#3: Doing very well (ironically had the least and shortest treatment)
Me: Adv Labs positive 2016 (suspected I passed to my kids) - not as sick as others, mostly battling fatigue and yeast issues
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