And on a side note, Igenex says that band 31 can cross-react with EBV. Honestly at this point, I am not sure if I would trust any testing!
I totally agree on not really trusting any testing. Even the CDC says that diagnosis is made clinically!
I thought it was rather odd - as if someone "got to them" for Igenex to suddenly come up with Band 31 cross reacting with EBV. There are many articles on file with PubMed that show that Band 31 is B.burgdorferi specific.
And, as much as I found that article that Mpos listed interesting, I don't trust their conclusions. Why? They believe that there are many false positives for Lyme, even though they themselves proved that sero-negative results didn't rule out B.b. infections.
Not that Minicoopergirl needs more confusion, but this is the best interpretation I have found so far, with supporting PubMed articles!! www.reocities.com/HotSprings/Oasis/6455/western-blot.txt
You can go there to find supporting Pubmed articles showing what these bands represent.
An IgM result means that you have an active infection. It once was thought to mean an 'early' infection, but has since been revised. IgG means that the infection is at a later stage.
The more +'s you have beside a number, the stronger the reaction.
IND means indeterminate - not negative, but not quite strong enough to be "fully positive". But it means that you reacted on those bands and should be considered, especially when they are Lyme specific bands.
A "Lyme specific band" means specific for Borrelia Burgdorferi, sensu stricto - Lyme disease in the strictest sense. There is only one
on the over 300 known strains of Lyme that is considered Bb, ss. Nothing else will turn a Lyme specific band positive other than Lyme disease - - even though there are over 100 different strains of Borrelia in the US that cause human illness.
My understanding for Bands 18 & 41 (whether in IgM or IgG) is that they are indicative of the tail of the bacteria, which can cross react with other Spirochetal bacteria such as Relapsing Fever, Pintas and Yaws, and Syphilis.
Besides band 41, you also had Band 58, which is likely Borrelia Afzelii - a strain typically found in Europe.
For those that were wondering about
the Band 31 articles:www.ncbi.nlm.nih.gov/pubmed/1520966www.ncbi.nlm.nih.gov/pubmed/9440203www.ncbi.nlm.nih.gov/pubmed/8406878www.ncbi.nlm.nih.gov/pubmed/8005219www.ncbi.nlm.nih.gov/pubmed/10030131
And more references can be found here:www.reocities.com/HotSprings/Oasis/6455/western-blot.txt