I've taken this from a Facebook post. In addition to the article he has posted a few great pdf's. For those not on Facebook I'm posting two links. The Facebook link and a link to them in an article that is much more scientific then the FB post where the charts aren't as user friendly.
"Many drugs compete for a family of metabolic enzymes in the liver that break down the drugs into harmless waste products. How long this process takes along with kidney excretion rates, determines a drug's half life.
When many drugs start competing for the same exact iso-enzyme in the liver, then drug toxicities can occur. The Cytochrome p450 Enzyme Drug Interaction charts can be confusing but can save lives.
Grape Fruit Juice is what brought the to the attention of pharmacists. A pharmacist about
30 years ago was taking Verapamil for blood pressure. When he took it with grapefruit juice his blood pressure bottomed out.
It turns out the grapefruit juice turns off many of the liver enzymes slowing drug elimination, this allows the drugs to accumulate until either toxicities occur, or the drug reaches overdose blood levels.
The opposite can occur when taking Rifampin. Rifampin is a liver enzyme inducer and potentiates or increases the liver enzyme effectiveness. This can mean other drugs are metabolized quicker and are less effective.
In Lyme disease it is good to know that many antibiotics interfere with newer non-drowsy antihistamines, and anti-fungal drugs causing serious heart palpitations, bradycardia and tachycardias.
Reviewing your meds on a drug interaction chart is always a good thing to do. Not all side effects are herxheimer reactions".www.aerzteblatt.de/int/archive/article/128426/www.facebook.com/groups/261243560639881/861027233994841/?notif_t=group_activity
The FB post is dated 12/12. The charts are listed as pictures. The first picture says Cytochrome 450 2 D6 Drugs:The Breakdown
Post Edited By Moderator (Traveler) : 12/14/2015 1:52:57 PM (GMT-7)