I think it may only be helping those that actually have autoimmune actions going on in their body from Lyme and company - those that don't (just the symptoms, no autoimmune reaction) are likely the ones it's not working for - but that's just my 2 cents.
Here is one (of many) article on LDI (low dose immunotherapy) for Lyme: restormedicine.com/low-dose-immunotherapy-new-therapy-for-lyme-disease-treatment-available-at-restormedicine/
"Low Dose Immunotherapy (LDI) is a therapy that combines miniscule amounts of allergens with an enzyme called beta-glucuronidase. It has been developed based on Low Dose Allergen therapy, which has been used for several years to address allergies of all kinds (initially based on Enzyme-Potentiated Desensitization therapy).
The enzyme (beta-glucuronidase) potentiates the antigen allowing for a much greater benefit than with traditional forms of allergy therapy, with much lower concentrations of the antigen itself. The enzyme makes T-cells (a type of immune cell) pay attention to the antigen included with it, down-regulating the immune response to that allergen. It does not completely suppress immune function- we need our immune system to be function well, we just don’t want it to overreact to specific things.
In this therapy, the antigens used in the remedy are taken from multiple strains of Borrelia, Bartonella, Babesia and Ehrlichia – in fact, the Lyme mix contains over 70 strains of these various pathogens. They are dead antigens that are mixed together with sterile water, and then combined with the beta-glucuronidase enzyme just prior to administration. When they are given to the patient, they are in highly diluted concentrations, and different concentrations are given depending on the sensitivity of the patient. "
Herb only treatment for Lyme & Bart ended 12/11 - no active symptoms for 2 yrs -Herb only treatment for Babesia ended 12/12www.healingwell.com/community/default.aspx?f=30&m=2977364
Had Lyme, Bart, Babs, RMSF, Ehrlichia, Myco, Anaplasmosis, EBV
New Lyme case 8/2014 - Healed 1/31/15 - unknowingly had Asymptomatic Babs and Asymptomatic Bart, being treated now though (2/2016)