Just use caution with the tryptophan. Start very small. In these infections it can cause many changes in brain chemistry as we know and sometimes adding tryptophan can exacerbate the issue further. What happens is that it goes down the Kynurenine Pathway and can cause brain excitability, extreme nervousness, agitation etc. You definitely don't want to promote more issues. So essentially it can do the reverse of what Buhner says.
Thanks for the heads-up. Can you provide any links with this information? I'm intrigued.
And frustrated. The more I dig into Buhner's book, the more conflicts and/or concerns I'm finding. I'm kind of frustrated right now. : |
When I was working with a nutritionist and having insominia (not knowing the other things going on), she wanted me to try tryptophan. Something told me that was not going to be good for me, so I did some googling and speaking with my doctor about
it. He was the one who told me initially that tryptophan can go array. Anyway she reasearch further and shared this article with me. So based on the fact that she at least knew I was dealing with inflammation she agreed that my symptoms would just get worse. So no tryptophan for me.
I don't know why Buhner doesn't add in information about
this since most with Lyme and co's are dealing with inflammation. There are other scholarly reports out there, but I like the way Dr. Herberg (below) puts it in simple terms. He is very knowledgeable.
"So, the amino acid tryptophan can basically go down two pathways. Tryptophan can go down the serotonin and melatonin pathway. So tryptophan actually converts first into 5-hydroxytryptophan, which you probably know as 5-HTP. And then after 5-HTP, that converts to serotonin, and then serotonin converts into melatonin, so that’s that pathway.
Now, if someone’s chronically inflamed, if there’s inflammation from an infection or food sensitivities, from stress and things like that, the tryptophan is going to go down an inflammatory pathway they call the kynurenine pathway. Sometimes you will test kynurenic acid to see if it’s high. Quinolinic acid is the other one that’s produced when tryptophan goes down the inflammatory pathway. So if there’s chronic inflammation, your tryptophan is going to be robbed down the inflammatory pathway instead of going down the serotonin/melatonin pathway, and that’s why you develop the deficiency.
So, one of the worst things you can do is to take tryptophan if you’re chronically inflamed. So if the patient does not have any signs of inflammation, then tryptophan is usually safe. If there’s a lot of inflammation, you’re really just going to get worse, and that’s probably why some of you know that either you’ve taken tryptophan, or you know someone who has, and it really didn’t help, or just made them worse. So I just explained the reason for that, biochemically."
http://drhedberg.com/insomnia-webinar-causes-and-natural-treatments/Wow - thanks for the thorough information.
I admit - I'm getting frustrated trying to implement some things from Buhner's books. I didn't read about
any of this on tryptophan in his latest book. This is why I really would love to find somebody to help more with the herbal side of things.
Kid#1: Extremely sick for several years, very difficult to treat, improved now but not fully well
Kid#2: Very sick now despite being treated for years
Kid#3: Doing very well (ironically had the least and shortest treatment)
Me: Adv Labs positive 2016 (suspected I passed to my kids) - not as sick as others, mostly battling fatigue and yeast issues