ALA interferes with T4/T3 conversion.www.ncbi.nlm.nih.gov/pubmed/1815532
For those of us taking thyroid meds, this means you could need more T3.
I take synthetic T4 & T3 and started having trouble maintaining my optimal thyroid levels shortly after I started doxy ala my PCP. It could have been the doxy....the Lyme....or both.
My thyroid kept going low (and I'd increase my thyroid doses) throughout my treatment. I know I was/am taking stuff that could interfere with my thyroid levels.
My thyroid doctor understands this and has been working with me and giving me the dose adjustments I've needed.
It was only earlier this year that I went hyper on meds and needed dose DEcreases. I've been somewhat stable these past few months and consider that a good sign for overall healing.
My issues have been all neuro. The benefits of ALA outweighed the risks for me. I take R-ALA for whatever it's worth.
Jul '14 tick bite - inadequate abx from PCP
Sept '14 met LLMD - clinical Lyme dx due to Bells Palsy/started abx (CDC positive IgM)
Feb '15 weaned off abx and started full Cowden protocol along w/LDN - 90% healed
Aug '15 started transition to Buhner's Lyme, Babesia & Bartonella protocols
Nov '15 stopped LDN - 98% healed
Aug '16 started modified Buhner Lyme/Bart protocol - 99% healed!