Mepron - Lots of questions

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Girlie
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   Posted 12/3/2016 12:25 AM (GMT -7)   
So, I have a bottle of Mepron to do a Babesia challenge (thanks to a very generous friend)

I know it won't be enough to treat...it will last approx. 3 weeks.

I have a lotta questions:

1) Take with fat. If I take it with a tsp of almond butter...and a handful of cashews...is that enough fat?

2) Can I eat my breakfast/dinner right after that?

3) Bottle says to keep it at 59 to 77 degrees F. Even after it's opened...it doesn't need to be refrigerated?

Protocol considerations:

Mepron plus Zith (I have about 3 weeks worth.)

Mepron plus biaxin (I have 3-4 weeks worth)

Mepron plus minocycline (5 weeks worth)


Wondering if I should do it daily...or pulse the way I've been with Bart treatment.

4) What do you think about adding the bactrim after two weeks of Zithro and mepron...to give it extra kick for the last week. (per LLMD MR)

5) If I pulse it...I could do a round of Artemisinin on the days off.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14; added biaxin Sept. 26/14 Disc. amox,added Ceftin Nov. 20th.; Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin); Abx/herb break Apr-July/15; July-mino; Aug. added Rif; Nov. switched mino to biaxin.

Huddie
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   Posted 12/3/2016 7:29 AM (GMT -7)   
Girlie,

Mepron does have to be taken with fat. I gave my son almond butter on toast and that is fine.

It works very well with Zithro and Mino - this is the three my son was given together.

We do keep in the fridge.

LLMD says NOT to pulse Mepron. You can do 5 days on/2 off but they just changed my son to 7 days on.

Hope this helps and let us know if it's working!

Mustard Seed
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Date Joined May 2016
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   Posted 12/3/2016 8:13 AM (GMT -7)   
Here we go:

1.) Aim for about 40g of fat per dose. In one study, atovaquone administered with 23g and 46g of fat led to 2.7- and 4-fold increases in AUC (blood concentration calculation) versus taking it without food, respectively.

onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.1994.tb04232.x/pdf

One tsp of almond butter has 3g of fat. Try to aim for more. 1 cup of whole milk has 8g, which is a good start if your diet allows for milk. Still though, the more fat you add, the less money you're peeing out.

2.) Yes, it's best to follow that up with a meal. There might be extra fat in your regular meal.

3.) Per the Mepron monograph, always store between 15-25 degrees C. Therefore, DO NOT refrigerate, NEVER freeze.

ca.gsk.com/media/591391/mepron.pdf

4.) Adding Bactrim is a very, very good idea. Most prominent LLMD's add it to Mepron/Zithromax. In the last few years, some have added the newer drug Alinia instead. Alinia can also kill broader parasites like some nematodes, and is very safe, with no P450 interaction. Both Alinia and Bactrim DS are highly recommended.

5.) You could pulse it, since Mepron does have a lengthy half life, and Babesia is slow-growing. The only advantage to this however, is that it saves money. I've never heard of any clinical benefits of pulsing Mepron, and I've never heard anyone recommend it.

If it were me, I wouldn't pulse it, as it's important to avoid resistance at all costs, especially with a front-line medication. If you're going to spend the money to do Mepron, you may as well take a full, legit shot at it.

Adding Artemisinin is a great idea. I've found Zhang Artemisiae-2 to be much, much stronger than regular Artemisinin from Allergy Research Group.

In his Babesia book, Dr. S talks about how regular Artemisinin is the weakest Artemesia derivative. His favourite appears to be Zhang's "Artemisiae", which contains artesunate. It's the most active and least toxic form of artemisinin. The "Artemisiae" formula is half the strength of Zhang's "Artemisiae-2" (a newer product that was released after the Dr. S book). "Artemisiae-2" contains straight dihydroartemisinin (the actual killer ingredient for Babesia, and what artemisinin and artesunate break down into).

It appears that these Zhang products do NOT need to be pulsed. While artemsinin decreases concentration in the body because of liver auto-induction, it's active metabolite, dihydroartemisinin, continues to increase regardless.

While Dr. S talks about artemisinin's tendency to be pulsed, he doesn't say anything about pulsing for any artemisinin derivatives. The only consideration to pulse these Zhang products seems to be to avoid toxicity over a long period like several months. Zhang himself recommends a 1 to 3 month treatment period. However, if doing it as an add-on with Mepron, you could very well pulse it.

BONUS POINTS:

Make sure the ferritin level in your blood is in the upper half of the range while on Artemisinin, as iron facilitates free-radical creation, which is what kills the parasites. If it's not up there, take Ferrous-heme (take ferrous heme with Vitamin C, and away from other minerals like calcium, zinc, etc., to facilitate absorption).

You should also be on anti-oxidants like NAC and others while on Artemisinin to minimize free-radical damage to other parts of your body, but try to take them away from the Artemisinin dose, so that they don't counter each other too much; you still want free-radicals smashing into the parasites.

Never take Milk Thistle, Rifampin, or Doxycycline at the same time as Mepron. They will all make Mepron concentrations plummet. I'm not sure about minocycline, unfortunately. Further research would be needed for that.

Zithromax is the only macrolide that has been proven in the literature to work with Mepron to kill Babesia. Many LLMD's suspect other macrolides, like Biaxin, will work too, but again, this is hearsay and hasn't been proven to the same extent in the literature as zithromax.

Lastly, some anecdotal advice: start Beyond Balance BAB-2. I find it produces a VERY strong herx. My LLMD says there is absolutely no substituion for this product. Dr. C says she finds BAB-2 to be hepful in about 80% of her Protomyxzoa Rheumatica cases (similar to Babesia).

Think that's it for now!

Oh one more thing: when doing Mepron, do it for at least 5 months. The parasite can hid in the blood cell for 4 months, so the extra month gives you some overlap. It also takes a few weeks for blood concentrations to rise to a killing level.

You should be on 750mg/5mL of Mepron twice per day minimum. Dr. S is finding that even this dose does not offer a cure in most of his patients, and advocates higher doses (make sure you're checking liver function!).

Also keep an eye out for RBC death in your labs, as well as decreases in neutrophils and increases in eosinophils. Any of these findings after starting Mepron would make me very suspicious of a Babesia infection.

Post Edited (Mustard Seed) : 12/3/2016 8:28:06 AM (GMT-7)


Huddie
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   Posted 12/3/2016 8:20 AM (GMT -7)   
Girlie,

I was told to take Mepron two hours from Zith. Also LLMD said that Alina makes you very dizzy so they like to avoid that one.

Anyway. Bactrim is ok to take with Mepron/Zith - that was another one they were thinking of for my son.

Mustard Seed
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Date Joined May 2016
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   Posted 12/3/2016 9:12 AM (GMT -7)   
Mister Mike said...
Awesome information Mustard Seed. Based on that info, especially about the possibility of an infection becoming resistant to Mepron if a full course isn't followed (3 weeks vs 5 months), perhaps trying BAB-2 first might be a good idea to see if she reacts?

I've long suspected a Babesia issue for myself, although have been trying to deal with other things first, but this is great info to have - thanks.


Ya, I'm not a doctor or anything, but I'd tend to agree with being weary of just doing a short course of Mepron.

To note, there really isn't any literature that supports Mepron resistance. We don't really know if it happens or not.

Regardless, it's highly unlikely you'd be eradicating an infection in that short a time span, that's for sure. It takes a few weeks for the atovaquone concentration in your blood to build up.

Girlie
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Date Joined May 2014
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   Posted 12/3/2016 11:11 AM (GMT -7)   
Thanks everyone....


Okay, so I will load up on fat, and eat a meal after.

My fridge is colder than 59 F....so will not refrigerate it. (I wasn't sure if those were "non-opened" bottle instructions)
I will not be able to have this in the summer months...Our house gets to 80 F for a few weeks.

I don't have and can't get Alinia...so it will most likely be Zith or biaxin plus bactrim with the mepron.

It's not for money-savings - my reason to pulse. It's because a) I only have one bottle and stretching it out will give me more time to convince my regular GP that I need to take it. ND's aren't able to prescribe anti-malarials.
Also - i have been following Dr. J's pulsing methods...he does pulse Mepron.

I'm not sure about the Artemisia - So there's Artemisia - whole herb...and then the Artemisinin, Artensuate, Artemether are the active constituents? Isn't artemether a pharma med?

My ferritin level is low - 45 and then 40 - my LLND doesn't want me to supplement...my GP does.
The GP likes to see it around 100. My RBC count and Hemoglobin are in range though.
So, if treatment kill red blood cells...I'm going to be in trouble. I will have to supplement before starting...

Can you take iron while on Mepron?

So, neutrophils and eosinophils are both part of the WBC count. Any reason why one drops and one raises potentially?

Minocycline is one of LLMD MR pairings with Mepron...so I'm thinking it's okay.


So bottom line is I only have the one bottle of Mepron. I am trying it to see if I have an obvious herx - as in air hunger...increase in sweats...so I can convince my GP to prescribe more
I have no other way....unless I go over the border and see a LLMD in Seattle. (and still no guarantees he will treat me for Babs)
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14; added biaxin Sept. 26/14 Disc. amox,added Ceftin Nov. 20th.; Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin); Abx/herb break Apr-July/15; July-mino; Aug. added Rif; Nov. switched mino to biaxin.

Mustard Seed
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Date Joined May 2016
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   Posted 12/3/2016 11:59 AM (GMT -7)   
Yes artemether is a pharmaceutical.

I'd probably supplement your iron. I'm not sure if this has a contraindication with Mepron unfortunately. I've never heard that it does.

If treatment kills red blood cells, it should be fine as long as you're doing blood work to monitor it.

I don't know why eosinophils and ECP tend to go up after starting treatment. This info comes from here:

www.personalconsult.com/articles/updated-babesia-textbook.html

and here:

/www.ncbi.nlm.nih.gov/pmc/articles/PMC1925019/

Good luck!

Huddie
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   Posted 12/3/2016 12:18 PM (GMT -7)   
Girlie,

My son was not told to supplement iron and he has to supplement a lot.

He didn't have any breathing issues from Mepron - he had/has non-stop cough, tightness in chest* and rib squeezing feelings -but not many of those.

*I think the chest tightness is from Zith. because I got that on zith.

Girlie
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Date Joined May 2014
Total Posts : 27959
   Posted 12/3/2016 12:20 PM (GMT -7)   
Thanks, Huddie.

I'm thinking maybe I should do a week or so of supplementing iron...and then start the Mepron.

I'm already low in Ferritin...

Have to think about that one.

As far as symptoms goes - I will watch for any new ones...or increase of old ones...
Fun times ahead!!!!
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14; added biaxin Sept. 26/14 Disc. amox,added Ceftin Nov. 20th.; Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin); Abx/herb break Apr-July/15; July-mino; Aug. added Rif; Nov. switched mino to biaxin.

Biaj53
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Date Joined Dec 2016
Total Posts : 5
   Posted 12/3/2016 2:03 PM (GMT -7)   
Hi guys

I'm being treated for bab/Bart. Plus Doc thinks I may have had old Bart from 2007.

Pharmacy said to store mepron in dark dry area and it doesn't require refrigeration. Just room temp.

Currently do 600mg Rifampin 1x day, 100mg minocycline 2x day, 250mg zithro 1x day, 750mg mepron 2x day and Nystatin 500k units 2x day. Also doing Bunher protocol for Bart and added in Atemisinin and grape seed as well as Olive seed and terminala (for bab candida and biofilm). Doing burbur milk thistle beta glucan magnesium and detox tea for detox and cell support. Also doing terminala and 2 Aleve a day for inflammation. And PROBIOTICS and multivitamins.

Has anyone here done higher doses of rifampin and mepron?

Seems to be working but very slow. 2 steps back 1 step forward 2 steps forward 1 step back etc...

was think about switching from Rifampin to Septra or Levoquine. Any thoughts?

Also HHV-6 showing inactive. RBC high WBC low waiting on CD 57 results and Dr just biopsied my bite area. When I get run down it grows and gets dark under skin. Crazy!! Got bit August 3 still have mark.

Btw first month and a half I just treated for Lyme. So got a late start on bab and Bart. Lyme treatment was Doxy flagyl ceftin clarothromycin- not all in that order.

How long until: breathing issue better? Burning in sides and armpits? Coughing and swollen esophagus and pressure in throat?

My bp normally 110-115/62. Has been 90/77 but finally getting better. 112/72 the other day.

Thanks all!

Girlie
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Date Joined May 2014
Total Posts : 27959
   Posted 12/3/2016 2:16 PM (GMT -7)   
Hi Biaj53, welcome to our community!

I was taking Rifampin 600 mg daily, but in two divided doses.


So, you are taking both Rifampin and Mepron together? I have read that taking Riffy can make the Mepron less effective.

Are you pulsing the Artemisinin? It should be.

Re: higher dose of Mepron. I have read one LLMD's protocols (he has an online lyme treatment book) - and he says after 1 or 2 months if no improvement with babs symptoms...to try 2 tsp twice daily instead of 1 tsp.

But, you said you're getting improvement...so your dosage may be fine.

If I were you I would continue with the Rifampin...I wouldn't do Levoquine (black box warning) unless I was desperate.
Septra is good, but I think Rifampin has more success - from what i've read/heard.

Treating lyme only for a month and a half isn't long...My LLND had me on lyme only abx for over 7 months, plus 2 I had done prior to seeing him....now that's long.

I can't tell you how long before those symptoms subside...but it isn't a quick fix...

Are you detoxing?

We encourage all new members to take a look through the thread at the top of the page titled: "New to Lyme?..Start Here!" It's packed full of useful information.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14; added biaxin Sept. 26/14 Disc. amox,added Ceftin Nov. 20th.; Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin); Abx/herb break Apr-July/15; July-mino; Aug. added Rif; Nov. switched mino to biaxin.

Post Edited (Girlie) : 12/3/2016 4:50:01 PM (GMT-7)


Huddie
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Date Joined Nov 2014
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   Posted 12/3/2016 2:19 PM (GMT -7)   
Biaj,

Hi. Welcome. Wow you are on a lot. You must be super duper strong. I envy those that can tolerate a lot and just knock it out.

From what I read on here it's pretty common for most of us to treat Lyme and then later treat cos. For us, we didn't we had cos until months later and we're chronic. So don't worry too much about the timing or the order.

Sounds like you are doing everything you can and making progress.

Lyme is definitely like a spiral straircase - not a direct healing route at all.

Hang in there sounds like you are doing great.

This post makes me realize how different LLMD's are. We were told to put Mepron in the fridge.

Biaj53
New Member


Date Joined Dec 2016
Total Posts : 5
   Posted 12/3/2016 4:17 PM (GMT -7)   
I actually didn't ask my Dr about it. The directions said to storeit at room temp. I asked 2 diff pharmacist and they both told me to store at room temp. So assuming that they are correct.

Yea. I think- hope I'm making progress. It is a lot. I got c-diff early on. So my dr put me on flagyl and actually extended it to get the cyst form. I've been documenting pretty good. I think it is important for all of us to document symptoms and photograph rashes on a daily basis. I know my Dr told me he didn't need to see test results to know I had Bart because of all the crazy stretch mark like rashes. I also had some crazy atypical rashes.

My Dr. Good guy follows Buhner, Horowitz, Burrascano


Just wondering when I'll breath normal again. The air hunger has been the biggest pain - and arythmias.

Post Edited By Moderator (CD3764) : 12/3/2016 4:26:23 PM (GMT-7)


Biaj53
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Date Joined Dec 2016
Total Posts : 5
   Posted 12/3/2016 4:22 PM (GMT -7)   
Hi
Yes I am detoxing. I use Yogi detox tea and some other supplements but I'm wondering if I should use clay or charcoal?

Yes the pharmacist said Rifampin can lower mepron a efficacy. I'm taking 2 tsp so I'm wondering if I should up dose or switch meds

They just biopsied my bite. So we will see if there is anything else.

My Dr thinks I was misdiagnosed in 2007 and have had a Bart strain since then, so this new strain mixed with bab is that much harder to deal with.

ID doc and old primary back then treated me for Lyme for 2 months. I still had symptoms though... pain in the soles of my feet bad! I could barely walk. But the ID Dr never tested me and told me it was prob lingering symptoms from campylobacter. I was 28 and healthy. I shouldn't have gotten campylobacter. So I prob got it cause I had Bart.

CD3764
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Date Joined Sep 2014
Total Posts : 4508
   Posted 12/3/2016 4:31 PM (GMT -7)   
Welcome Biaj53!

Sorry for the reason you're here but glad you found us.

Thanks so much for sharing all you did! It's great to know you're in such capable hands.

Unfortunately, since many LLMD's have been persecuted by medical boards and insurance companies, we don't allow sharing of LLMD's names/websites in the open forum. That's why I had to edit your post.

Hopefully, any member who might be interested in learning more about your LLMD can contact you privately. (when your email has been enabled via your profile).

Thanks so much for understanding!

Please be sure to let us know how we can help....even if it's just lending an ear.
Jul '14 tick bite - inadequate abx from PCP
Sept '14 met LLMD - clinical Lyme dx due to Bells Palsy/started abx (CDC positive IgM)
Feb '15 weaned off abx and started full Cowden protocol along w/LDN - 90% healed
Aug '15 started transition to Buhner's Lyme, Babesia & Bartonella protocols
Nov '15 stopped LDN - 98% healed
Aug '16 started modified Buhner Lyme/Bart protocol - 99% healed!

Pirouette
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Date Joined Mar 2014
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   Posted 12/3/2016 4:55 PM (GMT -7)   
For those of you using tinctures to provoke a response:

Just a quick note about Beyond Balance Babesia formulas - according to my nurse:

MC-BAB-1 is geared toward Babesia microti
MC-BAB-2 is geared toward Babesia duncani
MC-BAB-3 is geared toward "the others"

I've looked at other sources, which agree w/ BAB-2 and duncani but not very specific regarding the other versions of MC-BAB.

I was on Byron White A-Bab for a couple months at the beginning of my treatment - very difficult time. Then started taking it again a few months ago with very few problems. So I transitioned to BAB-2 with even fewer herxes. So I've decided to move on to BAB-3 and then I'll likely start Mepron or Malarone.

-p
Lyme Moderator
Chronic late-stage lyme—likely infected in 2000; Clinically dx Mar'14 w/ Babs, + for Bart, CDC + for Bb. Multiple viruses & GI/immune treated first; started AL-Complex in May, A-Bart & A-Bab in July; Nov'14 IV port installed-started Rocephin; added vancomycin Mar'16
DETOX: Pinella/Burbur/Parsley/Milk thistle/Burdock root; cholestyramine / jap. knotweed L-5-MTHFR LMN-V-II probiotic

Mustard Seed
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Date Joined May 2016
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   Posted 12/3/2016 5:15 PM (GMT -7)   
Wow great info on the Beyond Balance. Is there a different symptom picture between the various strains? What's their geographic location?

Pirouette
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Date Joined Mar 2014
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   Posted 12/3/2016 5:28 PM (GMT -7)   
MS -
I'm not sure. Good question. I've not heard or read much distinction other than response to testing/therapy. But I think it's wise to expect that Babs has evolved and mutated just like Bb has.

Here is more info:

Beyond Balance MC-BAB-1
Ingredients:
– Red Clover
– Rue
– Wormwood
– Prickly Lettuce
– Valerian
– Nettle

Properties:
– Anti-bacterial
– Anti-parasitic
– Anti-viral
– Anti-microbial
– Anti-inflammatory
– Anti-septic
– Designed to work with Babesia

Beyond Balance MC-BAB-2
Ingredients:
– Comfrey
– Burdock
– Blessed Thistle
– Stevia
– Motherwort
– Wild Yam
– Plantain Leaf
– Damiana

Properties:
– Anti-bacterial
– Anti-parasitic
– Anti-viral
– Anti-microbial
– Anti-inflammatory
– Anti-septic
– Unique to Babesia duncani and other Babesia strains

Beyond Balance MC-BAB-3
Ingredients:
– Wild lettuce leaf
– Parsley leaf
– Mistletoe herb
– Eucalyptus leaf
– Valerian root
– Cat’s claw bark
– Yucca root
– Stevia leaf
– Blessed thistle herb

Properties:
– Anti-bacterial
– Anti-parasitic
– Anti-viral
– Anti-microbial
– Anti-inflammatory
– Anti-septic

Byron White A-Bab
Ingredients:
– Gou Teng
– Cat’s Claw
– Noni
– Sam Bong
– Neem
– Curcuma Xanthorrhiza
– Yarrow

-b

Post Edited (Pirouette) : 12/3/2016 5:38:12 PM (GMT-7)


Rikky1
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Date Joined Jun 2015
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   Posted 12/3/2016 6:03 PM (GMT -7)   
I treated Babesia Duncani for almost 10 months with Coartem, Alinia, Mepron, Malarone, Zithro, Cryptolepis and Byron White A-BABS, still showing up in my blood. Nasty little critter it might be cause my Bart was in the way we'll see once I get that under control (if ever!)

Bactrim definitely has action against Babesia I had a nasty herx when I first started it a while ago got these huge bags under my eyes and they got all itchy.

>>Babesia is slow-growing

i've read in quite a few places that babesia reproductive lifecycle is anywhere from 2-6 days.

MustardSeed is spot on with all the other stuff posted. Good one to bookmark!

Girlie
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Date Joined May 2014
Total Posts : 27959
   Posted 12/3/2016 6:19 PM (GMT -7)   
Rikky - When you were on Mepron, what else were you taking? Any other anti-malarials?

Did you do the Coartem and Alinia separately?
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14; added biaxin Sept. 26/14 Disc. amox,added Ceftin Nov. 20th.; Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin); Abx/herb break Apr-July/15; July-mino; Aug. added Rif; Nov. switched mino to biaxin.

Georgia Hunter
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Date Joined May 2012
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   Posted 12/4/2016 5:23 AM (GMT -7)   
Good post Mustard. I like the recommendation of using the BAB-2 as a challenge instead of the Mepron. There is quite a bit of evidence of resistance to Mepron.

onlinelibrary.wiley.com/doi/10.1111/j.1939-1676.2009.0300.x/full

cid.oxfordjournals.org/content/50/3/381.short

aac.asm.org/content/46/5/1163.short

Huddie
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Date Joined Nov 2014
Total Posts : 3126
   Posted 12/4/2016 7:33 AM (GMT -7)   
Great post - Pirouette thanks for the BB listing. I didn't know that about the different strains of Babs.

What if we don't know.

Mustard Seed
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Date Joined May 2016
Total Posts : 1164
   Posted 12/4/2016 8:12 AM (GMT -7)   
Georgia Hunter said...
Good post Mustard. I like the recommendation of using the BAB-2 as a challenge instead of the Mepron. There is quite a bit of evidence of resistance to Mepron.

onlinelibrary.wiley.com/doi/10.1111/j.1939-1676.2009.0300.x/full

cid.oxfordjournals.org/content/50/3/381.short

aac.asm.org/content/46/5/1163.short


Good stuff!

Rikky1
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Date Joined Jun 2015
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   Posted 12/4/2016 8:27 AM (GMT -7)   
Along with Zith/Mepron I also did Zhang's Artimisaie. I did 2 stints of 3 months each. Weaved somewhere in there (not at same time) I also did a few rounds of Coartem where you have to stop everything a few days before, during and after. After Zith/Mepron I did a few rounds of Alinia (3 consecutive days a week) along with Zith/Tinidazole the other 4 days.

I got herxes from Coartem and Alinia but they were both short lived. Also had a herx from Plaquenil but also short lived (e.g. a day or two).

Biaj53
New Member


Date Joined Dec 2016
Total Posts : 5
   Posted 12/8/2016 9:39 PM (GMT -7)   
Wow! Rickky

How long did it take for Babesia to go away?
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