Sorry it's been such a long time! Someone referred to me as a "consummate caretaker" awhile back based upon what was going on in my life at the time. It's still the same and perhaps more so. Thus, my continued absence from the forum - sorry.
Thankfully, my healing continues on deeper levels...and I doubt a healthy person would even question my daily experiences.
I never forget you guys and that's why I'm posting right now.
All of that said, I've been looking to save money on supplements (my wallet is so very sore). I started to research nutritional yeast thanks to a recent thread by PeteZa.
I found that many of the nutritional yeast products list "folic acid" as an ingredient.
Since I am hetero for the C677T MTHFR mutation, I've been taking folate (vs folic acid) ever since I learned about
the mutation. I've also been taking methylated B vitamins.
Anyway, I emailed NOW Foods to question their nutrition fact listing for their nutritional yeast - one of the listings is "folate (folic acid)".
I found their response quite intriguing....and I copy and paste it here:
" Federal Nutrition Labeling regulations require listing foods fortified with folic acid in the manner listed on labels. Our supplier (Red Star) adds synthetic folic acid to the formula.
Should you require a more detailed explanation regarding folic acid safety see below:
Folic acid is synthetic. But, whether you take food folate or folic acid, the body synthesizes a third, active form from it. Folic acid is twice as bioavailable and twice as effective at raising the body's level of that active form than food folate (per the National Institute of Medicine's Food and Nutrition Board). The notorious lack of bioavailability of vitamins from food matrices, and the need to convert them to the body's preferred forms, is why the well-absorbed isolated form is used in food fortification and supplements. Here is some additional information if interested:
The MHTFR issue is not directly related to the form of folate taken since it is actually referring to the internal production of a weaker version of the enzyme from any form of folate due to the genetic issue. Those who use this to imply that folic acid is ineffective are not reading the science carefully. The safety and public health benefits of folic acid cover decades of rigorous research and are indisputable. /ods.od.nih.gov/factsheets/Folate-HealthProfessional/
Dietary folates, including methylfolates, are converted to folic acid during digestion, so folic acid is the usual form after digestion (even for most methylfolate supplements) until the body re-methylates it:
Folates only work in the body as the active methylated form. If one doesn’t have high homocysteine levels or anemia, then by definition they have adequate conversion to methylfolate AND production of sufficient MHTFR enzymes even if the enzymes are weaker than normal.
Theoretical manipulations of data to suggest that folic acid is harmful defy not only the evidence of public health studies but the extensive literature reviews utilized to establish ULs and safety. It would be impossible to address every sensational and theoretical issue. Much of what we hear about
methylfolates is marketing-driven by pharmaceutical companies holding patents on those forms, using selective data. Their not-unbiased trainings have influenced a number of doctors, with buy-in from those few supplement companies who have licensed their products and also have a vested interest in presenting incomplete data to support their product sales.
Folic acid “is reduced, within the cell, to the metabolically active THF form.” Measuring intestinal conversion is not necessarily the whole story. www.ncbi.nlm.nih.gov/pubmed/20608755
Folic acid has a robust safety record as a safe, non-toxic dose and higher levels are more likely to support good health if a person has the genetic issue (SNPs) where their MTHTFR enzyme is weaker than usual. This is because the extra folic acid also converts into 5-MHTF, the precursor of MHTFR, and thus creates an appropriately larger pool of the enzyme to allow proper detoxification of homocysteine, etc. even with weaker enzymes being produced. ghr.nlm.nih.gov/gene/MTHFR
“Regardless of whether you have an MTHFR mutation in both genes or not, the treatment for elevated homocysteine is the same—dietary intervention and supplementation with folic acid and vitamins B6 and B12. The amount of each of these supplements should be adjusted on the basis of the degree of homocysteine elevation, not your genetic status. If you have mutations in both MTHFR genes but have normal homocysteine levels, you do not need to be on folic acid or vitamin B6 or B12 therapy." circ.ahajournals.org/content/111/19/e289.full
Here are the only proven benefits of methylfolate over folic acid:
“Studies comparing L-5-methyl-THF and folic acid have found that the two compounds have comparable physiological activity, bioavailability and absorption at equimolar doses. Bioavailability studies have provided strong evidence that L-5-methyl-THF is at least as effective as folic acid in improving folate status, as measured by blood concentrations of folate and by functional indicators of folate status, such as plasma homocysteine. Intake of L-5-methyl-THF may have advantages over intake of folic acid. First, the potential for masking the haematological symptoms of vitamin B(12) deficiency may be reduced with L-5-methyl-THF. Second, L-5-methyl-THF may be associated with a reduced interaction with drugs that inhibit dihydrofolate reductase.” www.ncbi.nlm.nih.gov/pubmed/20608755
NOW Product Information Dept.
Information in this response refers to products labeled for sale in the U.S.A. unless otherwise indicated."
Comments always welcome ;)
Jul '14 tick bite - inadequate abx from PCP
Sept '14 met LLMD - clinical Lyme dx due to Bells Palsy/started abx (CDC positive IgM)
Feb '15 weaned off abx and started full Cowden protocol along w/LDN - 90% healed
Aug '15 started transition to Buhner's Lyme, Babesia & Bartonella protocols
Nov '15 stopped LDN - 98% healed
Aug '16 started modified Buhner Lyme/Bart protocol - 99% healed!
Post Edited (CD3764) : 12/30/2016 3:30:14 PM (GMT-7)