I have beaten lyme (and so has my daughter) basically with homeopathy and energy medicine.
I think homeopathy is one of the main tools I still use against infections, due to nosodes (that can be used without side effects from drugs). But not all homeopaths use nosodes, some are even against them, so...
In my opinion (based on our experience), nosodes, if well used, beat antimicrobial drugs by far.
Without Borrelia nosodes, I would be still fighting lyme disease and lyme relapses. Only nosodes stopped our relapses.
Here in Germany, Austria, Switzerland, Belgium, many people use homeopathy and homeopathy is much older than our current 'western medicine'.
I don't think I would be well today without homeopathy, herbs, energy testing and acupressure.
Drs treating chronic lyme do not have to use necessarily drugs, and some drs (like the one to whom I owe great part of my health) don't even think drugs are helping much lately...
Herxes can happen very fast after herbs or nosodes.
I'm currently on a special nosode preparation done specially for me by a Russian scientist, and boy, I'm herxing in so many joints... It's just experimental, but I guess, it's getting fungi deep inside my joints.
As for too many blood tests, well, if you have time and money, do them all.
If not, treat them anyway. If you are sure to have Borrelia (lyme), you probably have co-infections such as Bartonella and Babesia (the most common ones).
I would save my money to use for treatment, because even if tests come negative, there are still chances you have an active infection and will need to treat them, anyway.
When I was not sure I had babesia despite having almost all babesia symptoms (low iron, night sweats, hot flushes, extreme fog, extreme fatigue, light sensitivity, etc), a 3 day treatment of Riamet proved I had a protozoan, because all my symptoms vanished in those 3 days, after intense herxes.
Of course, I was not cured, as most symptoms returned a couple of weeks after that.
But at least, I was sure I had to look into anti-protozoan protocols.
Same for Bb: despite negative Westernblots, I had clear improvements with amoxi, and later, when I added Buhner's herbs, I improved certainly well. Even if they did not cure me, I knew I reacted to many anti-borrelial treatments.
Talking about Penicillin, I'm taking it exactly now, in that 'energetic-homeopathic 'mixture (mixed with candida albicans and parapsilosis). I'm taking Penicillium roquefortii , use to balance the intestinal flora.
I started yesterday, no big changes. Now, less than 48 hours after, boy, I'm herxing. And this is just an imprint of nosodes.