clavulanic acid is quite toxic to the kidneys. That being said, with or without the acid, amoxicillin will not reach your brain, unless you take 6g a day. and you cannot take augmentin in such doses because u will ruin your kidneys.
so good plain old amoxicillin is good but in very high doses.
alternative is use bicillin LA shots: better on stomach, they provide a steady stream of penicillin which is VERY EFFECTIVE for lyme. much better than amoxicillin, another penicillin.
penicillin in general has short half life so it gets excreted too fast from your blood stream. this is particularly a problem because lyme is a SLOW GROWING bacteria, so u need MIC levels for long time to achieve killing. this is why bicillin LA is so good, it produces a steady stream of penicilin in the blood stream that lasts for days after one single injection. so u need a few injections per week.
Some fine points made by mpost. Furthermore, for those who are self treating (never recommended), if you require more amoxicillin you can add it to the same amount of Augmentin and it will still do the trick as each drug has a different action.
Be sure to add up the amount of Amoxicilin in the Augmentin to your calculations. 3 is the max daily limit used with Augmentin although I have used 4 on occasion extremely short term (one day).
I never succeed in reaching a 6g oral dose as my body couldnt handle that quantity even in divided doses, although this might more achievable today, but I dont know.
Post Edited (ChickenArise) : 9/25/2017 11:25:05 AM (GMT-6)