l-tryptophan is converted to 5-htp before its converted to serotonin and melatonine. But there is a difference.
["5-HTP and L-Tryptophan are two great supplements for improving your mood and helping with healthy sleep. Your body converts both of these supplements into serotonin. However, your body must first convert L-tryptophan into 5-HTP before you can use it to make serotonin.
To answer the question of L-tryptophan vs 5-HTP, we found that 5-HTP is more effective in delivering high-quality effects and benefits than L-tryptophan. L-tryptophan can be thought of as a milder, more mellow form of 5-HTP with better results for improving sleep. 5-HTP, on the other hand, delivers a potent and effective mood boost but is not as effective at promoting sleep.
L-Tryptophan and 5-HTP must both cross the blood-brain barrier to deliver serotonin to your brain. L-Tryptophan has to compete with other amino acids to cross the blood-brain barrier. 5-HTP is better at this and more effective.
The conversion of L-tryptophan to 5-HTP is the slowest part of the serotonin pathway (the rate limiting step). This means that when you take L-tryptophan not as much serotonin can be produced as quickly as when you take 5-HTP.
Your body uses Tryptophan in a number of different methods to produce lots of compounds. These include proteins, NAD/NADP, Tryptamine and Niacin (metabolites). However, 5-HTP is only used to produce serotonin and melatonin.
Your body can convert L-Tryptophan and 5-HTP to serotonin in the liver and also in the brain. When L-Tryptophan has to compete with other amino acids to cross the blood-brain barrier, it has more of a chance of being converted to serotonin in your liver. Serotonin made in the liver doesn’t give you the mood-lift effects."]
Post Edited (astroman) : 12/7/2017 7:12:04 PM (GMT-7)