Lyme bug stronger than antibiotics in animals and test tubes. Now study people.

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sharo
Regular Member


Date Joined Oct 2017
Total Posts : 49
   Posted 11/11/2017 11:00 AM (GMT -7)   
Interesting article re persistent Lymes

https://www.huffingtonpost.com/entry/lyme-bug-beats-antibiotics-in-animals-and-test-tubes_us_59fa4fdbe4b09afdf01c4023

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 27285
   Posted 11/11/2017 12:42 PM (GMT -7)   
I quickly read the information - I don't think this is anything new - we've known about the persisters/biofilms...etc for several years now.



"I asked Paul Auwaerter, president of the 9,000-member IDSA and a Lyme physician-researcher, if the literature review suggested Lyme disease can be chronic and that additional antibiotic rounds may sometimes be needed. He wrote in an email: “There is yet to be a compelling reason to shift recommendations regarding treatment at this time. Clinical trials would be needed to see if different antibiotic strategies, for example, during treatment of early Lyme disease has any impact on people who go on to develop longer-term symptoms.” Many Lyme scientists and advocates are clamoring for such trials. Results of the last such trial, one of four in the U.S., were published in 2008."

"There is no ‘compelling reason to shift recommendations regarding treatment.’ — Paul Auwaerter, president, Infectious Diseases Society of America.
Auwaerter was a co-author of a 2015 Johns Hopkins article with Zhang that reported the challenge of killing Lyme cells by dosing the organisms with various antibiotics and other drugs. “The work I have participated was all in vitro,” Auwaerter wrote, referring to test-tube experiments, “so certainly far from the human condition as these were manipulated cultures.”"



No compelling reason to shift recommendations? Okay - let's just abandon the sick people....
What an a--h---.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

sharo
Regular Member


Date Joined Oct 2017
Total Posts : 49
   Posted 11/11/2017 1:32 PM (GMT -7)   
Unfortunately, i am unaware of some of this stuff, being a newbie to some of this information. Abandoning appears to be the general concensus and for me, it leaves me feeling Whats the point"!

Girlie said...
I quickly read the information - I don't think this is anything new - we've known about the persisters/biofilms...etc for several years now.



"I asked Paul Auwaerter, president of the 9,000-member IDSA and a Lyme physician-researcher, if the literature review suggested Lyme disease can be chronic and that additional antibiotic rounds may sometimes be needed. He wrote in an email: “There is yet to be a compelling reason to shift recommendations regarding treatment at this time. Clinical trials would be needed to see if different antibiotic strategies, for example, during treatment of early Lyme disease has any impact on people who go on to develop longer-term symptoms.” Many Lyme scientists and advocates are clamoring for such trials. Results of the last such trial, one of four in the U.S., were published in 2008."

"There is no ‘compelling reason to shift recommendations regarding treatment.’ — Paul Auwaerter, president, Infectious Diseases Society of America.
Auwaerter was a co-author of a 2015 Johns Hopkins article with Zhang that reported the challenge of killing Lyme cells by dosing the organisms with various antibiotics and other drugs. “The work I have participated was all in vitro,” Auwaerter wrote, referring to test-tube experiments, “so certainly far from the human condition as these were manipulated cultures.”"



No compelling reason to shift recommendations? Okay - let's just abandon the sick people....
What an a--h---.

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 27285
   Posted 11/11/2017 2:07 PM (GMT -7)   
sharo said...
Unfortunately, i am unaware of some of this stuff, being a newbie to some of this information. Abandoning appears to be the general concensus and for me, it leaves me feeling Whats the point"!

Girlie said...
I quickly read the information - I don't think this is anything new - we've known about the persisters/biofilms...etc for several years now.



"I asked Paul Auwaerter, president of the 9,000-member IDSA and a Lyme physician-researcher, if the literature review suggested Lyme disease can be chronic and that additional antibiotic rounds may sometimes be needed. He wrote in an email: “There is yet to be a compelling reason to shift recommendations regarding treatment at this time. Clinical trials would be needed to see if different antibiotic strategies, for example, during treatment of early Lyme disease has any impact on people who go on to develop longer-term symptoms.” Many Lyme scientists and advocates are clamoring for such trials. Results of the last such trial, one of four in the U.S., were published in 2008."

"There is no ‘compelling reason to shift recommendations regarding treatment.’ — Paul Auwaerter, president, Infectious Diseases Society of America.
Auwaerter was a co-author of a 2015 Johns Hopkins article with Zhang that reported the challenge of killing Lyme cells by dosing the organisms with various antibiotics and other drugs. “The work I have participated was all in vitro,” Auwaerter wrote, referring to test-tube experiments, “so certainly far from the human condition as these were manipulated cultures.”"



No compelling reason to shift recommendations? Okay - let's just abandon the sick people....
What an a--h---.


This is why we see the LL Dr.'s. Unfortunately, many (most?) of us don't realize that's what we need until years down the road.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi
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