Help interpreting Igenex results (and next steps?)

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hoosiercj
New Member


Date Joined Nov 2017
Total Posts : 2
   Posted 11/14/2017 2:32 PM (GMT -7)   
Hi, I'm a new poster, but frequent lurker (you guys are so helpful!), and I’m looking for help interpreting my Igenex results (and just general advice on next steps). Thank you in advance!

Background info: Multiple tick bites in my life (live in rural area in the woods), started to get very sick this summer with dozens of weird and seemingly unrelated symptoms, the most severe of which were heart palpitations, extreme anxiety and panic attacks, rapid weight loss, numbness in limbs, and shortness of breath/air hunger. Neighbor was diagnosed with Lyme this summer.

Testing info: Had two LabCorp Western Blots six weeks apart, and both came back negative. Family doctor agreed I had some kind of infection (consistently high WBC), and that it might be Lyme, but wouldn’t pursue it any further. Moved onto a LLMD, who ordered the Igenex test. Met with him today to get the results, and they are equivocal (see the full bands listing below).

Diagnosis? Next steps? My LLMD was ready to go ahead and diagnose me with Lyme based on my symptoms and an equivocal test before I walked in the door, but I’ve been getting better, and the second he heard that I wasn’t just totally miserable anymore, he decided on a wait-and-see approach. I do feel almost back to normal. I’ve done a lot of dietary changes, herbal immune support, and lifestyle changes over the past two months which may have impacted my improvement and/or test results.

He mentioned that Lyme can be very cyclical and goes into hiding, and with an absence of symptoms and an inconclusive test, he’d prefer to wait to start any kind of Lyme-specific treatment. Instead, he wants to focus on healing my leaky gut and yeast overgrowth issues. Which, I know, also will help fight the Lyme if it is there.

He did give me instructions for the herbal protocol he wants me to start on if my Lyme symptoms were to come back—so I do have that information available to me.

So my questions:

(1) Do you agree that my Igenex results are inconclusive/equivocal? I tend to see these results as an indicator of something, I’m just not sure what.

(2) Since I am feeling better, is there any harm in the wait-and-see approach? I’ve had a full workup done by multiple medical professionals, and I’m “healthy”.

Thank you so much!
-CJ

-------------------------------------------

Western Blot IgM
34 — IND
41 — +
58 — +
83-93 — +
(all other bands negative)

Western Blot IgG
41 — +
58 — ++++
83-93 — IND
(all other bands negative)

CD57 Absolute Count — 38
CD57 % Lymphocytes — 1.48

Negative serum tests for Babesiosis, Ehrlichiosis, and Bartonella

goshawk
Veteran Member


Date Joined Sep 2016
Total Posts : 1190
   Posted 11/14/2017 4:12 PM (GMT -7)   
Hi and welcome to our forum,

I am sorry you are having symptoms , but I am glad you have joined us.

Others are better than I about the testing but if you go to our"New to Lyme" start here thread at the top of the page it has information on what the bands mean.

I now that I only had a + for 41 and I have Lyme and co infections.

Healing your yeast/gut issues is very important since the Antibiotics may make it worse. Also the gut needs to be healthy to help us heal. Yeast can keep us from healing.


Many do herbal protocols, so that may be an option .

Others will be along to help out more, Take care, Jo

Post Edited (goshawk) : 11/14/2017 4:15:56 PM (GMT-7)


Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 27153
   Posted 11/14/2017 4:12 PM (GMT -7)   
Hi hoosiercj - welcome!


Multiple tick bites with those symptoms should warrant a clinical diagnosis of lyme disease.

PLUS this:

Western Blot IgM
34 — IND
41 — +
58 — +
83-93 — +
(all other bands negative)


+ on bands 41 and 83-93 should say Igenex positive on your test results.
Take a look.

I would not wait and see ... I would start treatment.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

hoosiercj
New Member


Date Joined Nov 2017
Total Posts : 2
   Posted 11/14/2017 4:38 PM (GMT -7)   
Thank you so much for your reply!

I was surprised to see "negative" for both Igx and CDC listed on the report for both IgG and IgM. It seemed to counterdict what they even listed as their definition of positive and negative.

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 27153
   Posted 11/14/2017 4:43 PM (GMT -7)   
hoosiercj said...
Thank you so much for your reply!

I was surprised to see "negative" for both Igx and CDC listed on the report for both IgG and IgM. It seemed to counterdict what they even listed as their definition of positive and negative.


I checked their website and found this:
"Positive If two or more of the following bands are present: 23-25, 31, 34, 39, 41 and 83-93 kDa.

Exception: Negative: If only bands 41 kDa and 83-93 kDa are present.

Indeterminate If only bands 31 and 41kDa OR only bands 31 and 83-93kDa are present."


So, I checked my test result sheet from a few years ago and it doesn't have that...so they've changed the criteria for a positive...
Sorry - I didn't realize that had happened.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 27153
   Posted 11/14/2017 4:52 PM (GMT -7)   
Band 83-93 is in Dr. Horowitz' list of significant bands when diagnosing lyme disease.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi
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