Mustard Seed said...
When you're taking Vitamin D, you're in-taking 25(OH)D. Your body then converts some of that to 1,25(OH)2D.
For some people, no matter how much Vitamin D they take, their levels of 25(OH)D don't go up.
Well infectious microbes down-regulate Vitamin D receptors (VDR). This in turn prevents 1,25(OH)2D from staying in a normal range, and your body begins to over-convert 25(OH)D to 1,25(OH)2D.
This is a brilliant strategy by the infectious microbes, as the increased amount of 1,25(OH)2D "further reduces VDR competence, suppresses macrophage function, and blocks the nuclear factor kappa-B pathway; thus inhibiting immune system function."
In short, the bacteria cause the body to over-convert one type of Vitamin D to another in order to shut off vitamin D-regulated immunity.
Olmesartan is indeed the medication used in the Marshall Protocol. There seems to be some scientific backing to his thinking, though I believe his protocol was a little more extreme, and included making sure the body doesn't intake any Vitamin D for a period of several years.
I wish there was more literature on Olmesartan for chronic stealth infections.
So, I'm thinking we should be getting both tests done. I've only had the 25(OH)D testing.
That doesn't tell me how much I'm converting to the 1,25(OH)2D.
MP was extreme. Wrap around sunglasses, long-sleeves in the summer. No exposure to sun...and yes, for several years.
I believe it also included low dose minocycline. (lower than what we take for lyme)
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi
Post Edited (Girlie) : 12/4/2017 3:09:26 PM (GMT-7)