Crossing the blood/brain barrier with Rx and herbs?

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

eldonkey
Regular Member


Date Joined Oct 2017
Total Posts : 82
   Posted 12/18/2017 1:15 PM (GMT -6)   
Hello Lyme world,

Been doing some reading on tiredoflyme today. Currently Im back in the doxy after taking a few days off (built up anxiety). Hit the alkaseltzer gold lemon concoction yesterday (minus the l glutathione) and it seemed to help. Anyway long story short many of my symptoms seem to be neurological..

Brain fog
Muscle twitching and spasms
Rapid heart beat as I awake
Dull minor heart ache when i lay in bed or on couch for a while
Anxiety
Depression
Bits of OCD

These symptoms align with my diagnosed proxymyzoa rheumatica

I understand now that doxy does not break the blood brain barrier. What are the risks of also adding amoxicillin to my regimen? Are there other natural herbs to try? I feel like this thing is mainly affecting my brain and if it's in there id like to kill it smile.

Thanks

Eldonkey

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 32622
   Posted 12/18/2017 2:27 PM (GMT -6)   
Just a quick reply - you could switch the doxy for minocycline for better b/b barrier penetration.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

eldonkey
Regular Member


Date Joined Oct 2017
Total Posts : 82
   Posted 12/18/2017 5:40 PM (GMT -6)   
Thanks Girlie!

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 32622
   Posted 12/18/2017 6:30 PM (GMT -6)   
I checked with the Drug Interaction Report for doxy and amoxy.

It did come up with Moderate - doxy may reduce effectiveness of amoxy.


But, I have to add that LLMD's sometimes do have two abx together with interactions like above.

For instance Doxy and Rifampin are sometimes paired together. And Riffy can reduce effectiveness of doxy.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 32622
   Posted 12/18/2017 6:31 PM (GMT -6)   
If I'm remembering correctly - Japanese Knotweed crosses blood/brain barrier good.


I did a search:


/www.healingwell.com/community/default.aspx?f=30&m=3727030
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

gfields
Veteran Member


Date Joined Oct 2015
Total Posts : 956
   Posted 12/19/2017 3:59 AM (GMT -6)   
I think I read a study that says rogaine opens the bbb.

eldonkey
Regular Member


Date Joined Oct 2017
Total Posts : 82
   Posted 12/19/2017 9:00 AM (GMT -6)   
Rogaine? Interesting.

gfields
Veteran Member


Date Joined Oct 2015
Total Posts : 956
   Posted 12/19/2017 8:35 PM (GMT -6)   
Ya, I think it expands blood vessels. It could be a double-edged sword though, because it could let more spirochetes in??

NW_Lyme_Guy
Regular Member


Date Joined Jul 2017
Total Posts : 33
   Posted 12/20/2017 8:35 AM (GMT -6)   
I was on a course of mino and it seemed to work well, but we had to switch after 45 days cause it was building up around my nerves. I was switched to another antibiotic. IMHO, you need more than one modality to get after these guys. ESP, if you have neuro symptoms.

Mine were really bad when I started treatment almost two years ago, and they’ve gotten way better. I couldn’t sleep, was having raging anxiety and panic, depression OCD and the like. There was no silver bullet or one antibiotic that worked, but combinations of herbs, enzymes, detoxifyers and antibiotics that slowly destroyed the pathogens day in and day out. Anyway, some herbs that may be useful: cats claw, gou teng, Chinese skullcap and Japanese Knotweed for sure. Blue sage is another one I’ve found good results with, but it’s hard to find.

Hope this helps....stay in the fight and you will get better. Find what works for your body, then take it back one day at a time.

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 32622
   Posted 12/20/2017 12:14 PM (GMT -6)   
NW_Lyme_Guy said...
I was on a course of mino and it seemed to work well, but we had to switch after 45 days cause it was building up around my nerves. I was switched to another antibiotic. IMHO, you need more than one modality to get after these guys. ESP, if you have neuro symptoms.

Mine were really bad when I started treatment almost two years ago, and they’ve gotten way better. I couldn’t sleep, was having raging anxiety and panic, depression OCD and the like. There was no silver bullet or one antibiotic that worked, but combinations of herbs, enzymes, detoxifyers and antibiotics that slowly destroyed the pathogens day in and day out. Anyway, some herbs that may be useful: cats claw, gou teng, Chinese skullcap and Japanese Knotweed for sure. Blue sage is another one I’ve found good results with, but it’s hard to find.

Hope this helps....stay in the fight and you will get better. Find what works for your body, then take it back one day at a time.


What do you mean "...it was building up around my nerves."

How was that determined?
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

eldonkey
Regular Member


Date Joined Oct 2017
Total Posts : 82
   Posted 12/20/2017 11:28 PM (GMT -6)   
Yes girlie I was going to ask the same thing. My neurological symptoms sound very similar to yours NW_Explorer. My symptoms include OCD, anxiety depression, all untriggered. Also head "numbness" and muscle twitching and weird heart rhythms.

A follow up question..of the herbs you mentioned, Are any COMMONLY known to give people bad allergic reactions? How are your symptoms now?

Spanish
Regular Member


Date Joined Sep 2017
Total Posts : 137
   Posted 12/24/2017 2:17 AM (GMT -6)   
Eldonkey, your symptoms sound exactly the same as mine. I have been taking mino for a couple of months now and it has made a massive difference. Id guess i feel around 70% better with all symptoms. However the muscle twitching did get a lot worse after i started treatment, I was prescribed an epilepsy med for this by my neuro who doesnt believe in lyme and it stopped the twitching over night. Interestingly i also use rogaine so dont know if this helped at all.

calande
Regular Member


Date Joined Dec 2008
Total Posts : 52
   Posted 1/6/2018 3:47 PM (GMT -6)   
Hello, as of today, do we know more on how to get antibiotics to pass through the blood brain barrier?
Lyme disease since early 80's | ELISA & Western Blot: Negative ; Elispot Borrelia: Positive
Current treatment: Texodil, Bactrim, Tetralysal, Zelitrex, Triflucan, Stevia Nutramedix

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 32622
   Posted 1/6/2018 6:54 PM (GMT -6)   
calande said...
Hello, as of today, do we know more on how to get antibiotics to pass through the blood brain barrier?


Well, you could use one of the ones that is better at getting through?

(like minocycline)


I heard an interview with THE Dr. J in Washington, DC and he said that's not something to be concerned about...which I found interesting ...to hear him say that.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

calande
Regular Member


Date Joined Dec 2008
Total Posts : 52
   Posted 1/7/2018 1:35 AM (GMT -6)   
Thanks, yeah, minocycline seems the best at crossing the BBB. Does it treat all forms of borrelia? (free, cysts, biofilms). If not, any other drug that both crosses the BBB and treat resistant forms of borrelia?
Lyme disease since early 80's | ELISA & Western Blot: Negative ; Elispot Borrelia: Positive
Current treatment: Texodil, Bactrim, Tetralysal, Zelitrex, Triflucan, Stevia Nutramedix

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 32622
   Posted 1/7/2018 3:20 AM (GMT -6)   
calande said...
Thanks, yeah, minocycline seems the best at crossing the BBB. Does it treat all forms of borrelia? (free, cysts, biofilms). If not, any other drug that both crosses the BBB and treat resistant forms of borrelia?


I don't think it's good for biofilms and cysts.

I've read Tinidazole (for cyst form) effectively passes thru b/b barrier.

I take Xylitol and Lactoferrin for biofilms. I don't know about b/b barrier penetration with them.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

calande
Regular Member


Date Joined Dec 2008
Total Posts : 52
   Posted 1/7/2018 3:40 AM (GMT -6)   
Thank you
Lyme disease since early 80's | ELISA & Western Blot: Negative ; Elispot Borrelia: Positive
Current treatment: Texodil, Bactrim, Tetralysal, Zelitrex, Triflucan, Stevia Nutramedix

sickoflyme123ct
New Member


Date Joined Jan 2018
Total Posts : 4
   Posted 1/8/2018 5:27 PM (GMT -6)   
In addition to crossing the bbb barrier, I just realized today that there's a vitreious fluid barrier in the eye. I was reading some reports today of certain abx being able to cross this and enter the vitreious fluid in the eye.
New Topic Post Reply Printable Version
Forum Information
Currently it is Friday, June 22, 2018 11:33 AM (GMT -6)
There are a total of 2,974,483 posts in 326,183 threads.
View Active Threads


Who's Online
This forum has 161254 registered members. Please welcome our newest member, herc.
404 Guest(s), 10 Registered Member(s) are currently online.  Details
jazzgtrl4, Froggy88, compiler, The Dude Abides, Girlie, Redwing57, Alex ArmPain, Herophilus, quincy, OriolCarol