"Black discoloration of the thyroid gland was first reported as a side effect of minocycline, a long-acting tetracycline antibiotic, in laboratory animals in 1967.1 The first human case of black thyroid was subsequently described in 1976.2 During the following 4 decades, approximately 125 cases of black thyroid have been reported in the literature.3–5 Black thyroid is asymptomatic, so the discolored gland is typically discovered incidentally during surgery or upon autopsy.6 Notably, black thyroid cannot typically be diagnosed by fine-needle biopsy.3
On gross examination the gland has a coal-black appearance (figure 1, A), which is virtually pathognomonic for long-term minocycline therapy."
Ultra Sounds are shades of black and white. The shades are "reflective" of the tissue density, just like other medical imaging. So this would not show up on US since its coloring not density change. Would only show in surgery.
Is doxy is the tetracycline family?
Yes, doxy is a tetracycline. So, I guess I won't know if my thyroid is black. Did you look at pictures? It looks gross...like charcoal...eeewww.
I haven't seen anything on doxy causing it though. so far - just mino. But, doxy doesn't cause the blue/grey color on our teeth...so doubt if it would discolor the thyroid black.
It's apparently not common though.... I tried to find information on whether it clears up over time once the mino has been stopped.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi