Wondering about when person is positive on all but one IGG bands and one IGM band

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New Member

Date Joined Dec 2017
Total Posts : 3
   Posted 12/22/2017 10:09 PM (GMT -6)   
Hello All!

I figured I would come to the group and ask a perplexing question.

How could someone be positive on all IGG bands but 23 and positive on that IGM band (23) ?

Is this even possible?

Any thoughts or hypothesis are welcome.

Forum Moderator

Date Joined May 2014
Total Posts : 33899
   Posted 12/23/2017 2:28 AM (GMT -6)   
Yes, it's possible.

I had bands on IgM that weren't on the IgG.

IgM means active infection.

oh, and welcome to our forum.

How long have you had symptoms? Are you currently treating?
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

New Member

Date Joined Dec 2017
Total Posts : 3
   Posted 12/23/2017 10:33 AM (GMT -6)   
Hello Girlie!

Hope you are doing well!

Lyme titre was over 11.

Symptom that brought me to the doctor's office 4 days ago was a swollen knee. I had s cartilage injury from a car accident so thought I may have reinjured it. I was swollen maybe 1 1/2 times normal.

It became warm to the touch. I developed a fever. My Lyme screen was over 11. Not one. Eleven.

Being acutely IGM positive on 23 seems reasonable enough although I do not remember being bitten.

What I am asking about is if anyone has any ideas or hypotheses on this

What could make someone IGG positive on ALL BUT ONE band (not 23) and active (IGM positive) on 23.

From what I read in my shocked and dazed state, people struggle to get diagnosed at all. 5 bands is not that common and I have or have had 10.

Looking for people's thoughts as to how someone could test like like that.

Symptoms:5 days swollen knee, fever (resolved)

Thanks for letting me post.


Veteran Member

Date Joined Aug 2017
Total Posts : 2026
   Posted 12/23/2017 12:40 PM (GMT -6)   

I had a couple thoughts after reading this. I have NO factual basis for thinking this and zero medical background. It just occurred to me that maybe you had past exposure to all the IGG positive components and your immune system took care of those. Maybe band 23 is a new exposure that you didn't have before OR your immune system simply failed to produce any protective antibodies against the band 23 component. (This is all completely off the cuff. I am not well versed on all the different bands and what they represent.).

I'm sure others will come along with much more intelligent answers.

Post note: Okay, I used the search button and found this reference in an old post regarding band 23: /www.ncbi.nlm.nih.gov/m/pubmed/8225587/

Post Edited (WalkingbyFaith) : 12/23/2017 10:56:06 AM (GMT-7)

New Member

Date Joined Dec 2017
Total Posts : 3
   Posted 12/23/2017 2:46 PM (GMT -6)   
Hello walkingbyfaith. I hope you are well!

Thanks for the link!

I am open to all thoughts. Thanks for your's!
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