YBX3 rs2305849 Involved in Lyme disease?! Does anyone understand what this means?

Are you homozygous for YBX3?
1
Yes - 25.0%
1
No - 25.0%
1
I don’t know - 25.0%
1
Homozygous what..?? - 25.0%

 
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Shellazae
Regular Member


Date Joined Jun 2017
Total Posts : 66
   Posted 1/12/2018 8:42 PM (GMT -6)   
Hi,
I came across something that said gene YBX3 is involved in Lyme disease. Umm.. ok not sure what this means but I decide to put the gene into my livewello sandbox and sure enough there are two rs numbers that show up and mine are both homozygous! It also says on livewello that it means I am antibiotic resistant. Anyone else heard of this??!

http://www.malacards.org/card/lyme_disease?search=TLR1

I am not getting much better, I wonder if this could be why.
Here is the other snp on livewello rs2418103

Post Edited (Shellazae) : 1/12/2018 6:59:25 PM (GMT-7)


astroman
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Date Joined Mar 2014
Total Posts : 5086
   Posted 1/12/2018 8:53 PM (GMT -6)   
www.malacards.org/card/lyme_disease?search=TLR1

Post Edited (astroman) : 1/13/2018 12:40:39 AM (GMT-7)


Shellazae
Regular Member


Date Joined Jun 2017
Total Posts : 66
   Posted 1/12/2018 9:07 PM (GMT -6)   
Astroman, did you reply with something? I can see that you hit reply but nothing is showing up, perhaps you still have it open.

astroman
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Date Joined Mar 2014
Total Posts : 5086
   Posted 1/13/2018 2:57 PM (GMT -6)   
I went into gene research mode and lost time. Just made a blue quick link.

Did not find much more info on this one. Must be newly found.

I did mine with Sterling app (about 300 genes), two years ago, and rs2418103 YBX3 is not even listed.

What heading was it under in your livewello report?

k07
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Date Joined Sep 2015
Total Posts : 2547
   Posted 1/13/2018 6:31 PM (GMT -6)   
I will check mine in livewello - hopefully will get to it tonight.

k07
Veteran Member


Date Joined Sep 2015
Total Posts : 2547
   Posted 1/13/2018 7:44 PM (GMT -6)   
I didn't see 2 SNP's, just used the one you listed. I was -/-

k07
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Date Joined Sep 2015
Total Posts : 2547
   Posted 1/13/2018 7:53 PM (GMT -6)   
Also, I recently did speak to a genetics person in regards to patterns seen in those with chronic lyme. I have all the usual issues - glutamate, iron, not able to clear hydrogen peroxide. He also mentioned he sees a pattern with those who have ATG13 gene - basically said these are the people who have a hard time digging out of a hole. I am heterozygous on all 6 of the SNP's for that gene. May be worth looking at too. I can list SNP's if you are interested.

Shellazae
Regular Member


Date Joined Jun 2017
Total Posts : 66
   Posted 1/15/2018 11:33 AM (GMT -6)   
Here are the Snps that pull up on livewello. rs778154538 rs2418103 rs777959791 rs781380503 rs2305849
I only have two with values.

rs2305849 TT
rs2418103 GG

I will go check the other gene.


Ps I made this search public on livewello, if you are a member there.

Post Edited (Shellazae) : 1/15/2018 9:50:13 AM (GMT-7)


Shellazae
Regular Member


Date Joined Jun 2017
Total Posts : 66
   Posted 1/15/2018 11:48 AM (GMT -6)   
Interestingly, this snp is listed by another member saying Lyme disease is antibiotic resistant with the following gene and rs. Let me know if anyone is homozygous.
TLR1 rs5743618

Shellazae
Regular Member


Date Joined Jun 2017
Total Posts : 66
   Posted 1/15/2018 11:56 AM (GMT -6)   
astroman said...
I went into gene research mode and lost time. Just made a blue quick link.

Did not find much more info on this one. Must be newly found.

I did mine with Sterling app (about 300 genes), two years ago, and rs2418103 YBX3 is not even listed.

What heading was it under in your livewello report?



YBX3 - LYME DISEASE RESISTANCE

k07
Veteran Member


Date Joined Sep 2015
Total Posts : 2547
   Posted 1/15/2018 11:58 AM (GMT -6)   
Shellazae said...
Interestingly, this snp is listed by another member saying Lyme disease is antibiotic resistant with the following gene and rs. Let me know if anyone is homozygous.
TLR1 rs5743618


I'm heterozygous on that one.

Shellazae
Regular Member


Date Joined Jun 2017
Total Posts : 66
   Posted 1/15/2018 12:00 PM (GMT -6)   



Interesting, it didn’t show this the other day, thanks for the link.

astroman
Veteran Member


Date Joined Mar 2014
Total Posts : 5086
   Posted 1/16/2018 10:18 AM (GMT -6)   
Shellazae said...
Interestingly, this snp is listed by another member saying Lyme disease is antibiotic resistant with the following gene and rs. Let me know if anyone is homozygous.
TLR1 rs5743618


Might be good to look for the notation on what lab proved this. Then goggle the lab for more info.
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