numbing in leg normal? berberine cause?

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Date Joined May 2017
Total Posts : 140
   Posted 1/24/2018 9:16 PM (GMT -6)   
So been feeling pretty well for a while now, even went to the gym 4 times last week, then added berberine to my regimen and took 2 the first day, 2 the second, but on day 2 I woke up with EXTREME fatigue. I felt terrible, could hardly get through the work day. Also had a slight numbing/tingly feeling in my left leg above my knee, outside quad the last two nights. This is a new symptom for me.

My question is, could just a couple of berberine set me off that bad and could it cause a numbing/tingling in my leg?? Is this a normal lyme symptom? I don't know if it's the berberine or just a bad flare set off by maybe overdoing it on the exercise or stress from work, etc.

It left me feeling a bit depressed because I was doing so well. Have been resting after work yesterday and today/taking epsom baths and activated charcoal and haven't taken any oil of oregano/berberine/anti virals of any sort. Just multi vitamin and turmeric as my inflammation has been really bad as well. I am going to take some MSM tomorrow as when I used to take that it seemed to help with inflammation/eye pain that I have that is now back. Feeling hopeless that life will never be normal again. Fine one day then BAM, it's back sad

Regular Member

Date Joined Jul 2015
Total Posts : 231
   Posted 1/24/2018 11:03 PM (GMT -6)   
I've had setbacks during treatment, don't let it discourage you. The delayed reaction sounds typical of a herx to me.

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Date Joined May 2014
Total Posts : 33965
   Posted 1/25/2018 1:45 AM (GMT -6)   
Hang in there, Raleighgirlie!

There are ups and downs along the healing path. You may have overdone the exercise last when you recover....maybe scale back a bit on your work-outs.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

Regular Member

Date Joined May 2017
Total Posts : 140
   Posted 1/25/2018 9:49 PM (GMT -6)   
Still exhausted today. I couldn't go to the gym if I wanted to the past few days lol. When I go, I only do like 2 miles on the elliptical, nothing crazy. I am not going to go this weekend even if I start feeling better. I am just going to rest.

I am wondering if maybe I am reacting to the berberine. I was taking berberine and oil of oregano and I don't normally have any drastic reaction to oil of oregano alone. I was taking the berberine for blood glucose but think I read it is also anti viral/bacterial/fungal so could this be a herx maybe from the berberine/oil of oregano combo? I quit taking it on Wednesday after I went downhill so fast on Tuesday. Maybe it really stirred the little buggers up. I haven't had this kind of fatigue since I did doxy. I have that gene that makes it harder for me to detox so have been trying to treat with supplements over abx since it's less harsh. Until now anyways...

Regular Member

Date Joined May 2017
Total Posts : 140
   Posted 1/26/2018 9:37 PM (GMT -6)   
Heard back from LLMD and she said I could definitely herx from berberine and I was taking 1000 mg so to back off. I guess that was just too much overload for me.

Confirming it was a herx means that the berberine is definitely killing off something pretty strong for me so makes me not want to stop it...I might just only do 500 mg and see what happens. I feel like such a little weakling being my body just shuts down on berberine or doxy it seems when I read about other people on multiple abx and herbs that are handling it all okay. How will I ever get rid of this if I can't even handle 1000 mg of berberine very well?
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