Please help - I have three (3) "Present" Igg's: P45, P30, and P23, but "negative"

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New Member

Date Joined Feb 2018
Total Posts : 6
   Posted 2/3/2018 3:32 PM (GMT -6)   

I'm new here so forgive me if this has already been addressed.

I am trying to figure out why my LabCorp test results (received today so I haven't spoken to dr. yet) show 3 Present antibodies: IggP45, IggP30, and IggP23. Under the heading, "Lyme Igg/Igm Ab" it states "normal," under .91 and under "Lyme Igg Wb Interp." and "Lyme Igm Wb Interp." it states, "negative." I would normally be relieved, but as I've got three "Present" Igg bands, I'm confused.

It's my understanding that P23, which I have "Present" bands for, is highly specific for the lyme parasite -- so that is why I'm confused it's a negative result. I am going to a lyme specialist to try to figure this out soon, but if anyone has any info on this, I would appreciate hearing all opinions.

Incidentally, last year I had 12 weeks of swollen neck glands and a sore throat that lasted equally as long. My primary care dr. refused to give me antibiotics (went twice during this 12 weeks for help). I finally ended up with an ear infection, went to one of those "urgent care" centers, got antibiotics, and my sore throat cleared up in 2 days. I started to get the sore throat again this fall. I've had weird recurring headaches over the last two years.

I got tested for lyme last summer after getting bitten by a deer tick. I am looking for that paperwork now but I remember it came back "negative," much to my surprise due to all my weird health symptoms. I am an avid gardener.

Last week, I found what I think was old evidence of a tick on my hand (it was a dark speck, and for months thought it was a freckle - the dermatologist missed it too), so this is what prompted me to get new lyme testing last week.

I've been to the cardiologist several times in the last two years from odd chest pain and heart palpitations. My brain fog is getting worse - as in I can't remember words on a daily basis, very frightening. I'm starting to realize that all this might be from Lyme, but the test result is confusing - I guess because I don't have 5 positive bands it's "negative"??

I'm excited to have found this website and will read as much as I can to learn more about lyme disease.

Thanks everyone, and best wishes to everyone on getting well!

Forum Moderator

Date Joined Sep 2016
Total Posts : 2305
   Posted 2/3/2018 4:04 PM (GMT -6)   
Hi and welcome to our forum GardenGirl12,

Your symptoms and struggles sound like what many of the members have gone though.

I would seek out an llmd(lyme literate MD) and we help you with that here if you haven't already found one.

You would need to en ale your email to receive response from members. You would do this in your profile.

You then would start a new post asking"Seeking an llmd in your area".

You can also email me and I will check my list and send you llmd's near your area if I have them.

We dont post full llmd's names and information here to protect them. We only post the famous ones that are already well known everywhere.

You can also go to to do a physician search for your area and they will email you some names.

We encourage all new members to read our new to Lyme start here thread at the top of the page. It has information on Lyme, testing, symptoms, detoxing and more.

I think Band 23 is specific to Lyme. The testing can be unreliable and the CDC standards are not correct. You don't need to have 5 bands o have Lyme.

You need to check out the for the correct standards. Lyme and co infections can be clinically diagnosed.

Others should be along soon that have better insight into your test results.

Take care, Jo

Elite Member

Date Joined May 2007
Total Posts : 36310
   Posted 2/3/2018 4:37 PM (GMT -6)   
Hi Gardengirl,
Welcome to the community! Jo posted some really good information for you.

As Jo said, the testing is not good, and the CDC is just wrong about needing 5 bands. This is a complex issue, but it started a while ago, when they chose to ignore certain bands on the Western blot in order to deny more Lyme cases. It happened during what is known as the "Dearborne conference" in 1998 (??I believe??).

Band 23 is highly specific to Lyme disease, it's one of the band that the only thing that makes it positive is the person having Lyme disease. So you are correct on that.

By the way, band 45 often appears for Ehrlichia -which is treated the same as Lyme, only it's not as stubborn to deal with. Usually several weeks of treatment clears it up.

Keep asking questions!! We are here to help as much as we can!
Herb only treatment for Lyme & Bart ended 12/11 - no active symptoms for 2 yrs -Herb only treatment for Babesia ended 12/12
Had Lyme, Bart, Babs, RMSF, Ehrlichia, Myco, Anaplasmosis, EBV
New set of infections 8/2014 - still treating.
Come visit me:
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