What about Biologics for Lyme Disease?

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Girlie
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Date Joined May 2014
Total Posts : 32617
   Posted 2/8/2018 11:34 PM (GMT -6)   
Man in remission (Crohn’s Disease) - participating in clinical trials with Biologics.
Wonder if this may be an option for Lyme?

nationalpost.com/sponsored/patient-diaries-sponsored/conquering-crohns-calgary-man-fights-back

“ Biologics are effective in treating moderate to severe Crohn’s disease because they work on the immune system to block the activity of specific proteins that are causing the inflammation — because these may vary from patient to patient, different biologics are effective for different individuals. “
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

bluelyme
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Date Joined Nov 2015
Total Posts : 4715
   Posted 2/8/2018 11:40 PM (GMT -6)   
In the cancer cds dude talks to russians about phage therapy that works well supposed ly they have a limited virus to kill borrelia ...but idk ...i got enuff of those unless it eats ebv too...lol

Oh u misunderstood. ..its probably just immunosuppressive meds to stop autoimmunity instead of going after the pathogenic cause ...

If anybody really has crohns please read dan bergys posts on ln he got rid of his with a gb4000 mopa and mms ...also put his wifes lyme in remission

Please dont do anthing ending in tab or hab ....in the commercials it says not to do with any ACTIVE INFECTION ...if you have tb its lethal ..etc ...many theumys kill slowly trying to allieate symptoms bu reducing the immune system?

Post Edited (bluelyme) : 2/8/2018 10:47:37 PM (GMT-7)


Girlie
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Date Joined May 2014
Total Posts : 32617
   Posted 2/8/2018 11:59 PM (GMT -6)   
Okay - so it’s immunosuppressing - well fagettabout it then. Don’t want to do that.

I thought maybe it was more like the LDI that was talked about a lot two years ago...

Not to replace killing the bugs - but settling things down after.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

Post Edited (Girlie) : 2/8/2018 11:05:49 PM (GMT-7)


Psilociraptor
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Date Joined Jul 2016
Total Posts : 1228
   Posted 2/9/2018 8:19 AM (GMT -6)   
Lol yeah biologics are in general pretty questionable. Biochemists act like everything that's over expressed needs to be attacked. Ie Humira is an antibody that blocks the inflammatory cytokine TNF-alpha which is present in high levels in several autoimmune diseases. It reduces symptoms but doesn't address the question of why someone is that inflamed in the first place, likely facilitating the progression of the underlying pathology through immune suppression. Side effects may include tuberculosis and cancer. A lot of fancy technology goes into making this stuff, but ultimately the therapies these folks come up with are often quite primitive in concept. I mean... something is too high - attack it. Something is too low - stimulate it.

straydog
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Date Joined Feb 2003
Total Posts : 16295
   Posted 2/9/2018 10:59 AM (GMT -6)   
The drug he trialed was Remicade which has been around for quite some time, it is not a new drug. The patent expired on Remicade & now there is a sister like drug called Inflectra, much cheaper. When you google Innovative Medicines Canada, this is nothing more than a testimonial from a patient, in other words he is is a source of advertisement for the pharmaceutical. His testimonial is old news, lol. A lot of people will participate in trials for various reasons such as they have no insurance or money, other medications do not help & that sort of thing.

The potential side effects of the biologics we see advertised on tv are extremely low. As usual they are required by the FDA to report any side effect while the drug is in the trial phases. Treatment has come a very long way for people with crohns & UC, & I for one am very thankful these drugs are available. I have a higher chance of getting ran over by a bus than dying from one of the bios.
Susie
Moderator in Chronic Pain & Psoriasis Forums

WalkingbyFaith
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Date Joined Aug 2017
Total Posts : 1680
   Posted 2/9/2018 11:28 AM (GMT -6)   
straydog said...

The potential side effects of the biologics we see advertised on tv are extremely low. As usual they are required by the FDA to report any side effect while the drug is in the trial phases. Treatment has come a very long way for people with crohns & UC, & I for one am very thankful these drugs are available. I have a higher chance of getting ran over by a bus than dying from one of the bios.


straydog,
The issue for us is we have active infections that could do increased damage if we suppress our immune systems. Do you have Lyme or coinfections?

straydog
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Date Joined Feb 2003
Total Posts : 16295
   Posted 2/9/2018 11:38 AM (GMT -6)   
WBF, no I do not have Lyme, I have crohns & UC unfortunately. With IBD's we basically have over active immune systems, the bios suppress it. Often, yes we do get infections with these diseases & can safely continue bios, depends on the type of infection. In no way am I saying bios would help with Lyme. That would be like comparing apples to oranges, lol. The title of the post caught my eye.
Susie
Moderator in Chronic Pain & Psoriasis Forums

Traveler
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Date Joined May 2007
Total Posts : 36310
   Posted 2/9/2018 12:20 PM (GMT -6)   
And we thank you for your input. While we (Lyme patients) do need to avoid suppressing the immune function, I often feel bad for those that need to take the risks of some of these new medications. I figure that they must really be in need of them if they are told about the possible side effects and still use them.
Herb only treatment for Lyme & Bart ended 12/11 - no active symptoms for 2 yrs -Herb only treatment for Babesia ended 12/12
www.healingwell.com/community/default.aspx?f=30&m=2977364
Had Lyme, Bart, Babs, RMSF, Ehrlichia, Myco, Anaplasmosis, EBV
New set of infections 8/2014 - still treating.
Come visit me: dogwoodtraditionals.freeforums.net/
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