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Regular Member

Date Joined Dec 2017
Total Posts : 84
   Posted 2/15/2018 10:04 PM (GMT -6)   
What are specific protocols for pulsing Doxy? I took Tetracycline instead for a long time b/c the only time I'd ever taken Doxy for a month, I felt like I was going to die the whole time, it just does something really toxic-feeling to me. However, I also felt like I needed to try again and needed the coverage, but five days back on and I'm back to feeling so horrible -- none of the other meds make me feel quite this bad, except maybe Mepron when I was on it for awhile.

Anyway, feels like the "normal" dose is just way too much for my body and yes, I'm doing a lot of detox strategies, anti-inflammatory supps, etc. If I'm going to try pulsing though I'd like to know what has worked best for others (mostly specifics: days on/days off, dosing, etc.).

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Date Joined May 2014
Total Posts : 33798
   Posted 2/15/2018 10:56 PM (GMT -6)   
What are you going to take with it?
I wouldn't pulse one antibiotic by itself.

After over a year on daily dosing I decided to pulse my abx for bartonella M/W/F and my LLND said it was fine. I don't think I took week long breaks I'm doing now. (A week or two off)
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

Veteran Member

Date Joined Feb 2017
Total Posts : 670
   Posted 2/16/2018 11:16 AM (GMT -6)   
Initially I took it 6 days a week 2x a day with tini 3 days a week. The last time I took it, again with tini, m-w-f.

I think it's good to listen to your body. Maybe try every other day for now? Are you taking herbs or anything else with it?
MTHTR single mutation; Positive Igenix IgG Jan 2017; March/Apr '17: doxy, Tinizadole. 5/1 samento and mino/tini. 5/28- back to doxy, added activated charcoal. 6/9 - stopped antibiox; staying with samento, red root and houttiya and supps. tried LDN; 8/24 rifampin, samento, red root and supps. On and off rifampin. 1/1/18 - 1/20 rifampin. Herbs and vitamins only now.

Regular Member

Date Joined May 2016
Total Posts : 219
   Posted 2/16/2018 3:40 PM (GMT -6)   
I'm doing Sapi's protocol minocycline 100 bid and pulse with tindamax STRONG researched supported.

Regular Member

Date Joined Apr 2017
Total Posts : 172
   Posted 2/16/2018 5:36 PM (GMT -6)   
Kct said...
I'm doing Sapi's protocol minocycline 100 bid and pulse with tindamax STRONG researched supported.

Hello Kct. Can you please elaborate on this protocol ?
Do you pulse both the minocycline and the tindamax ? How exactly ?
Do you have a link to this specific Eva Sapi study? Does the study mention the effectiveness of a pulsed antibiotic therapy?
Thank you.

Regular Member

Date Joined Dec 2017
Total Posts : 84
   Posted 2/17/2018 5:24 PM (GMT -6)   
Hi all, I'm on a lot of other meds and herbs. Rifampin which I tolerate *great,* Ceftriaxone (IV), and herbs including now: cat's claw, houttuynia, and mimosa pudica (for babs). I seem to tolerate most other things okay though actually can't do tinda or Flagyl as Flagyl gave me severe peripheral neuropathy so I'm off all of those drugs. Do take oregano for cyst busting, along with grapefruit seed extract and some other things for biofilms.

So really its just Doxy that's a big issue for me for some reason.
I'm definitely intrigued by Sapi's protocol as I really respect her work, but wonder if there's a substitute for the tinda that she recommends since I can't take that?

It does sound like every other day could be good for me, I'll try that. Just noting, this is after several yrs now on Rifampin plus tetra (which I tolerate well); just for some reason Doxy is a real nightmare, and I feel liek I'm not getting enough results without it.
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