I'm not sure if you can compare the two for a certain symptom.
The antibiotics work differently - depending on what your particular symptoms are, and what infections you have.
I think the only way you'd know is to try each one.
The sensation you are now experiencing may be a herx from the minocycline.
Are you on Rifampin with it?
You may need to take a day or two break to let things subside.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi