(A little background info on my story which I've told before, otherwise you can just scroll to the bottom)
After treating Lyme with Doxy 200mg 2x/day, Azithromyicin 500mg 1x/day, and Tindamax 500mg 2x/day 3 days on/4 days off for a little over 3 months, I achieved about
an 85% improvement in symptoms, most of that gained in the first 3-4 weeks. I received an equivocal score of 20 for Babesia Duncani via igenex testing and on Jan 19th began treatment for Babs with Mepron 750ml 2x/day and Azithromyicin 500mg 1x/day, plus Tetracycline 500mg 3x/day (to switch up from the doxy). I took my first dose on a Friday night and by Saturday afternoon I had a 2-3hr period of significant depression that came and went but scared me, and I also spent that weekend on the couch due to dizziness and light-headedness. After that, I was able to tolerate things fairly well, I went to work on Monday and other than some increased anxiety over my baseline here and there, I had no major problems.
As detailed in my previous thread here: https://www.healingwell.com/community/default.aspx?f=30&m=3968709 around week 3 I noticed a significant uptick in anxiety that my Klonapin .25mg 3x/day was not touching, and by the end of the week 4 I had to stop everything, l had bad headaches especially near my temples, light headedness, fatigue, severe crushing anxiety and the feeling like I was weak and may faint. It is exactly what I imagine hell to be like. Chalking this up as the dreaded babs herx.
After a week of being off Mepron and the other Abx (except for mon and tues when I restarted the Zith and low dose of doxy 100mg 2x/day) which was absolute hell and focusing on detoxing via Alka Seltzer gold, drinking a lot of water, an Epsom salt bath, etc, when I woke up on Thursday I felt like my normal self. However, I started to get a weird sensation around the front of my forehead around lunchtime and about
an hour later while driving home had a near-fainting episode where I barely made it into the parking lot. I talked to my LLMD and he advised me to go home and start taking the Mepron and Zith again rather than go to the ER but I decided to go to ER anyways just to be safe. Bloodwork was fine except my sodium was slightly low at 129, EKG fine, and CT scan of head fine. The same near fainting episode in September before I had found out I had lyme is what triggered everything and led me here on this journey. (I had MRI, CT scan, bloodwork, EEG, Echocardiogram all after that to rule out anything else).
I basically feel like I did prior to beginning treatment (severe anxiety to the point my body almost convulses, irritability, fear of leaving the house), except now for the last 2 weeks I've added poor appetite and, worst of all, feeling like my brain/personality have been altered to the point where I find that I have to fight like heck to act normal. Pressure in the head comes and goes, too. I restarted Mepron and Zith Thursday night after getting back from the ER, but I didn't take the Friday morning dose as I wanted to ease my way back in for fear of depression, herxing, etc. Last night scared the living crap out of me, as a wave of depression hit me in the evening and I felt like as was about
to lose control of myself. I slept it off and vowed never to take the Mepron again (and now try to plow through like I did initially) as it is just too much to handle. I sit here feeling worse than before I started treatment as I think the medicine basically stirred up the babs that was basically dormant (I had no night sweats, air hunger, etc, but now I am starting to see those) with my biggest concern being the continued affects of my personality as well as crippling anxiety
Now then, what other options are there for treatment? I see my LLMD on Tuesday. I know the next antibiotic is Malarone, which I would be willing to try. Are there IV drugs or other combinations of oral ABX that have worked for anyone? I haven't tried the herbal route yet. Injections? (my buddy who had lyme and babs was getting Bicilin injections, I think). I have been able to work and tolerate everything up until this past week. I am most concerned about
getting my mind back, I can deal with air hunger and night sweats. I almost regret trying to treat this nasty bugger at this point. In the meantime, I am going to continue with the Doxy (will up to the 200mg 2x/day dose tomorrow) and Zith and keep up with some of the supplements of B vitamin complex, omega 3, magnesium, turmeric, L theanine, Alka Seltzer gold, and probiotic.