Minocycline one or two

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OriolCarol
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Date Joined Dec 2017
Total Posts : 728
   Posted 2/26/2018 1:48 PM (GMT -6)   
Minocycline is prescribed 100mg twice a day. I would like to know the average life of the mine. They say that to be effective it must have high concentrations in blood, then ... would not 200mg be better than once a day?

OriolCarol
Veteran Member


Date Joined Dec 2017
Total Posts : 728
   Posted 2/26/2018 2:09 PM (GMT -6)   
And another doubt i keep minocycline in fridge, is it safe?

tickbite666
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Date Joined Mar 2014
Total Posts : 1664
   Posted 2/26/2018 2:09 PM (GMT -6)   
that was my dosage as well (1) 100mg twice a day.

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 33909
   Posted 2/26/2018 2:12 PM (GMT -6)   
The half-life is 11-16 hours or 11-22 hours - I've seen both.

So, it's not a really short half-life.

I've not known anyone to take the 200 mg once daily.

If you take it 12 hours apart...you still have half of the previous dose in your blood most likely. (by the time you take the second dose)

I would stick to 100 twice daily unless a LLMD is telling you otherwise.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 33909
   Posted 2/26/2018 2:12 PM (GMT -6)   
Why do you keep it in the fridge? Is your house really hot?


Our house gets warm/hot in the summer months, but I still don't refrigerate it.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

OriolCarol
Veteran Member


Date Joined Dec 2017
Total Posts : 728
   Posted 2/26/2018 3:21 PM (GMT -6)   
Yes, we live in an atic and it's hot but i think no to hot to put in the fridge jajajaj

But is dangerous refrigerate it?

Spanish
Regular Member


Date Joined Sep 2017
Total Posts : 146
   Posted 2/26/2018 3:37 PM (GMT -6)   
My Llmd said it it was ok to take 200mg at once if I could tolerate it.

I do this in the evening which makes it easier to keep up with probiotics the rest of the time

Sheeks175
Regular Member


Date Joined May 2016
Total Posts : 284
   Posted 2/26/2018 3:44 PM (GMT -6)   
My LLMD prescribed 200mg 2x/day. Double the standard dosage. It's a doozy, but tolerable, and blood labs are normal.
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