Bands 41 and 58 IGG reactive?

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New Member

Date Joined Feb 2018
Total Posts : 10
   Posted 3/2/2018 2:14 PM (GMT -6)   
Have been having many lyme symptoms for the past two months. Was treated with 6 weeks doxy last June after a bullseye rash and positive IGM. Symptoms started again early January, was put on 30 days of doxy and plaquenil....felt worse all throughout treatment and still feel pretty terrible. Got Western Blot done 3 days after stopping abx through Quest diagnostics. Negative results for lyme, but reactive bands 41 and 58 Igg. Babesia test came back negative as well. Symptoms include tingling, burning in legs and feet, numbness, pain all over, throbbing, twitching, headaches, fatigue, muscle spasms, brain fog, stiff legs, muscle weakness, off balance, easily out of breath and hard to catch it again. Can it still be lyme with negative tests?

Forum Moderator

Date Joined May 2014
Total Posts : 33798
   Posted 3/2/2018 2:38 PM (GMT -6)   
Yes, it can be Lyme with a negative result.

This is why retesting isn't worth it.
You have relapsed so you need to get back on treatment - but not mono therapy now that it's a chronic infection. You will need a LLMD to get the appropriate abx for treatment now.

Quest isn't a good place to test anyway.

Sorry you have relapsed.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

Regular Member

Date Joined Sep 2017
Total Posts : 394
   Posted 3/2/2018 4:59 PM (GMT -6)   
Your symptoms are very very similar to what mine were. I would say highly likely you are experiencing a Lyme relapse. The tick bite that gave you the rash may have also transmitted other infections that do not respond to doxycycline. You say you never really felt any better through treatment.

You would be wise to seek effective treatment for all potential TBI's tick borne infections.

You will probably need to get an appt with a Lyme literate doctor to even be taken seriously. Most doctors are afraid to treat Lyme unless you come in with an active rash. Most of them will declare you "cured" from your previous course of doxycycline. I suspect they may not even clinically evaluate you or look at your symptoms. You could try your luck, but I wouldn't roll the dice if I were in your shoes. I would get to an LLMD asap!

People here can help you find one.

You can start a new post - "Looking for Lyme Literate doctor in "your city/state""
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