I've had excessive twitching in my calf for a few years now. Got worse once treatment started. It is still there, but more intermittent now. The weird thing is that the twitching started before my tick bite in 2016. I believe I already had some sort of infection that I was unaware of before the tick bite. Even though the twitches are intermittent now, when they do kick off, they can be anywhere instead of just the calves. But, my calves get them the most and most intense.
It could be benign fasciculation syndrome or just the bugs or die off messing with your nerves. Just go with it. Only control what you can control. No sense in worrying about what is out of your control. One thing I have learned with all this is that new symptoms will come and go. It's easier to roll with the punches than to take em tensed up. So, relax a bit. Stress can sometimes cause them to be worse.