I think The half life of Rifampin is 4-6 hours (I will check later - I’m laying in bed now)
Even though riffy may reduce effectiveness of doxy - some LLMD’s do pair them together.
I know sometimes Rifampin is dosed 600 once daily but haven’t seen doxy taken 400 once daily.
Maybe ask your dr about
taking the riffy say at 8:00 a.m and doxy at noon- by the time you take doxy...the blood levels of riffy will be lower (maybe only half) and my not have as much effect on the doxy.
Evening dose could be 5:00 and 9:00.
Not sure if it would make much difference tho.
Again - a discussion with your Dr - tell him your concerns
EDIT - to correct - i had mixed up the doxy/rif originally.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi
Post Edited (Girlie) : 3/12/2018 10:50:04 AM (GMT-6)