I've had a reaction to trimethoprim which was very similar to how Bactrim
(sulfamethoprim + trimethoprim) affected me. My doctor put me on trimethoprim alone to test whether the reaction to Bactrim was a sulfa allergy.
Days 1-4: 100 mg. Pressure around eyes, lymph nodes start to mildly ache, brief small lights in vision.
Days 5-7: 100 mg BID. Evening restlessness, pins and needles in webbing of fingers, muscle twitching, peripheral neuropathy flare, cognitive impairment.
After my second dose on the 7th day the symptoms became severe. There was migrating pain in joints including wrists, mostly knees; migrating burning pain in muscles; headache like I had been hit in the head; sinus pressure; migrating pain in tendons; strong tingling in areas of existing neuropathy; raw pains in cheeks and mouth (this made me worry about
I skipped my morning dose, and all of the symptoms have gotten much better over the last 15 hours. I've been diagnosed with Lyme, bart, and babs. What puzzles me is that I've taken augmentin for a sinus infection and had no issues with my knees. I think I'm going to ask my doctor to switch me to another class of antibiotic if this wasn't definitely a herx.
My detox is Kudzu root, 250 mg ALA BID, 600 mg NAC BID, Pinella/Burbur, epsom baths, serrapeptase, and vitamin C; I'm also on Buhner herbs. I'll update this thread tomorrow after I consult with my doc.