"T-Cell-Independent Responses to Borrelia burgdorferi Are Critical for Protective Immunity and Resolution of Lyme Disease"/www.ncbi.nlm.nih.gov/pmc/articles/PMC101777/
This is interesting. Mice with lyme bacteria and low T-cell response have arthritis.
".......Immunocompetent mice develop a consistent pattern of events following infection with B. burgdorferi. Within several days, local invasion and spirochetemia result in the evolution of arthritis and carditis, which peak within 2 to 3 weeks and then undergo immune-mediated resolution with bouts of recurrence over the course of 1 or more years of persistent infection (1, 7, 10).
Infection of severe combined immune deficient (SCID) mice results in persistent active carditis and progressively destructive arthritis........."
Goggling this, I see there are a few universitys (John Hopkins is one) researching T-cells and lyme and genes, which is great.
I made a post about
genes that express/effect T-cells last month, 23andme can identify some of this.
Post Edited (astroman) : 3/20/2018 2:02:40 PM (GMT-6)