I wouldn't worry about
it because it is a known IV antibiotic for lyme..so it should do the job.
It seems that there's conflicting info on which ones do pass the b/b barrier.
LymeMD says Penicillin does...but I was told it doesn't.
He also says Cephalosporins "do not do as good a job'
He states doxy and mino do, but macrolides don't much.
Flagyl and Tinidazole do a good job.
Here's what he wrote about
I haven't talked about
Rocephin, our favorite intravenous Lyme drug. It is a cephalosporin. Above I state above this class of drugs generally has poor penetration into the brain. Apparently some cephalosporins penetrate better than others. Literature about
Rocephin is mixed; but contrary to many claims, it does pass the blood brain barrier. Let me mention that Rocephin is used a lot for meningitis. In typical meningitis with active inflammation, there is a breakdown of the BBB and most antibiotics penetrate. With typical chronic Lyme, neuroborreliosis patients, there is no active inflammation. High doses of the drug, with high serum levels obviates the BBB problem. Rocephin is generally tolerated at high doses. Rocephin has other favorable properties: the long half life with once daily dosing, makes it easy to use this effective intravenous therapy at home. Even though some oral medications have better penetration through the BBB: the IV route makes Rocephin work better.lymemd.blogspot.ca/2013/03/blood-brain-barrier.html
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi
Post Edited (Girlie) : 3/22/2018 4:56:59 PM (GMT-6)