Compiting for one reason.

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Veteran Member

Date Joined Dec 2017
Total Posts : 730
   Posted 4/22/2018 6:52 PM (GMT -6)   
There are some studies that have shown that administering several antibiotics or drugs at the same time, can make them compete with each other ... Is there a competition between mino and rifampin for crossing the blood brain barrier? That is, can one molecule prevent the other from penetrating? I'm not worried about this, it's curiousity but it would be interesting if someone can contribute information.

Veteran Member

Date Joined Dec 2017
Total Posts : 730
   Posted 4/22/2018 6:57 PM (GMT -6)   
there is some study in lancet, for example that shows that amoxicillin works better without probenecid, because when both are administered, both compete to enter the bbb and one molecule, overlaps the other.

Forum Moderator

Date Joined May 2014
Total Posts : 33957
   Posted 4/22/2018 8:52 PM (GMT -6)   
I haven’t seen anything about the abx competing with each other.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

Regular Member

Date Joined Apr 2018
Total Posts : 187
   Posted 4/22/2018 9:33 PM (GMT -6)   
If so can you take 2hr apart so the other get into the bb
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