Cytochrome p450

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OriolCarol
Veteran Member


Date Joined Dec 2017
Total Posts : 563
   Posted 4/26/2018 3:46 PM (GMT -6)   
Today a nonun llmd doctor has told me that i was making a mistake when taking minocycline with rifampicin, because according to the minocycline is also affected by cytochrome p450 and acts like doxycycline .. he told me that the dose I take, i only absorb 40%
Is this true? I have not found anything about it on the internet. Is there any study that verifies this?

Missouri
Regular Member


Date Joined Sep 2017
Total Posts : 337
   Posted 4/26/2018 4:37 PM (GMT -6)   
I am inclined to believe him. Everything I read says is induces several enzymes more than any other substance. The enzymes neutralize many medicines.

OriolCarol
Veteran Member


Date Joined Dec 2017
Total Posts : 563
   Posted 4/26/2018 4:53 PM (GMT -6)   
If you put doxycycline and rifampin in google, there is a lot of evidence of the problem, but if you put minocycline, rifampin, you will not find anything ...

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 32672
   Posted 4/26/2018 5:29 PM (GMT -6)   
I’ve never seen anything about minocycline being on the Cytochrome p450 list.

I don’t think it is
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

Post Edited (Girlie) : 4/26/2018 5:42:54 PM (GMT-6)


Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 32672
   Posted 4/26/2018 5:37 PM (GMT -6)   
Here’s a chart

www.thblack.com/links/RSD/8_drug_interactions_table.pdf

I’ll try to find the thread on it - it was discussed awhile ago - 2016 I think.

There are some herbs on the list too... was it Cryptolepis or ?
Artemisinin may be one as well
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 32672
   Posted 4/26/2018 5:42 PM (GMT -6)   
/www.healingwell.com/community/default.aspx?f=30&m=3881828
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

OriolCarol
Veteran Member


Date Joined Dec 2017
Total Posts : 563
   Posted 4/27/2018 10:55 AM (GMT -6)   
I think the same... that there is not an interaction but minocycline is the brother of doxy... so i thought that it could interact simillar.

Girlie
Forum Moderator


Date Joined May 2014
Total Posts : 32672
   Posted 4/27/2018 11:19 AM (GMT -6)   
OriolCarol said...
I think the same... that there is not an interaction but minocycline is the brother of doxy... so i thought that it could interact simillar.



Nope, don't think so...same class, but different antibiotics.


- the same with Macrolides: Clarithromycin on the list, but NOT Azithromycin.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi
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