Herxing can happen immediately as well. I've had some that build up a d some that happen within minutes. Usually it builds up a d then each additional dose happens within minutes. As if there's a threshold you have to get to. But regardless, this is usually not so difficult. A herx will be similar to the symptoms of your own disease, will be dose dependent, and provided enough time will generally go away as your body detoxes.
A herx can also be new symptoms appearing.
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi