Interestingly when I plug lorazepam with Rifampin into the drug interaction checker - it says no interactions.
This checker usually does pick up on the p450 interactions...
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But lorazepam was listed on another site that showed interactions with p450 meds. I can't seem to paste the link to the site here.
the half-life of rifampin taken 300 mg dose is 3-4 hours
Are you taking the benzos once a day? Maybe if Rifampin is taken in the morning...even if there is a drug interaction...it would be reduced substantially by the evening. (12 hours apart)
A 600 mg dose of Rifampin has a half life of 5 hours - so if you do a once daily dosing - then that may be the better option. Take Riffy in the morning, benzo in the evening?
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi
Post Edited (Girlie) : 5/16/2018 12:21:32 PM (GMT-6)