To a much degree. But I really think everyone will extract the value out of optimized D25 levels. I view the studies quoted above as an independent validation of Marshall work(the one where they compare TLRs expression vs seasons is a unique).
Unfortunately, I did not find the study where they directly measured the increase/decrease of b.b. load as a result of D3 supplementation, but I've found the one where increased mortality vs toxoplasmosis was detected in mouses which immune cells were treated with 1,25-dihydroxyvitamin D3(active form of d25): https://www.ncbi.nlm.nih.gov/pubmed/15939587/
The authors concluded that this could be due to "inhibition of Th-1-type cytokines" but the thing is immunocompetence against b.b.(and many other infections) relies on Th-1-type cytokines too and vit d25 levels(via D3 supplementation/sun) inhibit Th1 cytokines: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633636/
Just my basic understanding...
Post Edited (Dmitry) : 9/13/2018 4:14:19 PM (GMT-6)