After taking antibiotics for a year, this has killed off the majority of the bacteria, such that I now get very little herx from taking antibiotics. At this point, I'm getting more adverse effects from the antibiotics than from Lyme disease. I still do get the occasional herx though, suggesting that the infection is not completely gone, and could come back if I stop the antibiotics.
My question is what is the best way to get rid of the last few bacteria so I can finally be done with this.
Currently I am taking clarithromycin, amoxicillin, and valproate.
Clarithromycin and amoxicillin mostly just cause diarrhea. Valproate has some rather annoying side effects. This drug is also used to treat epilepsy, but I don't have epilepsy, and am only taking it as an antibiotic to kill the bacteria. The neurologic effects of valproate are to me just unwanted side effects. It makes me feel a bit spaced out, and I really want to get off this stuff, but valproate is, by far, one of the most effective drugs at killing borrelia burgdorferi, and initially caused far more herx than anything else I took. It's a bit unusual in that it is very slow acting and took a couple weeks to accumulate enough to kill off the bacteria, which lead to some pretty uncontrolled herxing. Of course this is probably why it works so well. It stays around long enough that the bacteria can not just wait it out.
Maybe I'm asking in the wrong place, because it seems that most people only come here when they don't get better, and those who get better on antibiotics don't post here. So I'm hoping that there are actually people reading this who succeeded in getting rid of Lyme disease with antibiotics.
Daraprim, dapsone, and daptomycin have been mentioned. Did it work, and how long did you have to take these drugs to eliminate all the persistent bacteria? How do you know when it's all really gone, and where can I find a doctor willing to prescribe this? When I see people mention doctors here, it's always Dr. A, Dr. B, Dr. C... I have no idea who these doctors are.
Alternatively, could I actually get rid of all the persisters with valproate? The side effects of valproate are bad enough that I've had to temporarily discontinue it a few times, so I'm looking for an alternative, but I suppose I could try another month or two of valproate, along with the other antibiotics. Since a single dose of valproate can last for more than 24 hours, I suspect that taking it every day would eventually kill all the bacteria, but I'm not sure how long I'd have to keep taking it.
Hi Quin - welcome!
I’m a bit confused. Valproate is not an antibiotic - it’s used for treatment of manic depression -
(I also read it’s an anti seizure medication - something I didn’t know)
I’m not fully healed yet, but I’m on a persister protocol currently.
Dapsone, daraprim combined with other abx.
I’m having trouble with my email since I updated my operating system - but you can send me an email tomorrow - I may be back “online” by then.
We don’t mention the llmd’s full names for their privacy /protection.
Have you taken abx/anti malaria’s for Bartonella and Babesia?
(Amoxy and Biaxin aren’t effective )
The LLMD I see always treats Babesia early on.
There are people on here that are in remission or very close to it.
Generally people do stop posting regularly when they’re well but many come back now and then to say “hi”
Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi
Post Edited (Girlie) : 10/31/2018 8:29:07 PM (GMT-6)