MTHFR gene mutation

Here's one website (of many) with information on the topic: http://mthfr.net

At the top of the page, click the link for "Read This First!"

astroman said...
There are eleven versions of this gene.

...and, some 20,000 total genes in the human genome.

Here is a podcast with Ben Lynch, ND being interviewed on the topic of MTHFR, "Dirty" Genes, and more:

Dirty Genes, Overcoming Disease, & the Dangers of Folic Acid with Ben Lynch, ND
https://www.theenergyblueprint.com/dirty-genes-dr-ben-lynch
https://youtu.be/iakm6vfu79g

In this podcast, you’ll learn:

• What dirty genes are and how they affect us
  
• Which fatal disease the MTHFR gene protects you from
  
• Why folic acid can be dangerous to your health
  
• The first step in supporting your MTHFR gene
  
• Why Dr. Lynch was approached by a manufacturer, asking him to remove articles about folic acid
  
• How your mitochondria protect and keep you alive
  
• Why the GST and GPX (detox) genes are important for your health
  
• Why trying to fix your dirty genes is counterproductive
  
• The right way to take supplements for health and energy
  
• The first step you need to take to successfully clean your dirty genes

I have the C677T version and I didn't find out till I was 27 (I'm 28 now). My LLMD tested to see if I had it. All I do is try to stay away from foods that have the synthetic folic acid (enriched bread) and I take a pill once a day (L-methylfolate). I also switched to methylated b-vitamins so my body could process them. What type do you have? My doctor said that some types can have little to no issues while some like my double dose of c677t means I have to take meds. It really is not that bad once you get in the swing of it, and you will be amazed at how much more energy you have and how overall you feel better after just a few weeks on the pill (if you even have to take it). I always wondered why I had a hard time keeping my vitamin levels in range and had blamed it on Lyme for years. Now its like a whole new me. I finally managed to find a multivitamin that had methylfolate (smarty pants) and I have never been more excited to buy something. Anyone else find some they like?

Recently I went to a support group (in-person) for lyme and out of the 10 people there 7 had it. My personal theory is that people with MTHFR (and not treating) are already struggling to process necessary vitamins and such so that when they get infected with Lyme their bodies have a harder time fighting it off. This is just my opinion though.

Thanks so much for all the info everyone! Very helpful! I do have the double mutation. Do you know if (L-methylfolate is able to be purchased over the counter or do I have to go through my LLMD? I heard earring daily leafy greens is good for us, I do that anyway but I’m going to try to eat even more. Thank you all again!!!

https://www.google.com/search?client=safari&rls=en&q=methylfolate&ie=utf-8&oe=utf-8

---

Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

Thanks so much everyone!! Really appreciate all your help.
Does this mean I’ll be taking (L-methylfolate for the rest of my life then or just until I get over Lyme?

I was pretty healthy except I have some minor hormonal issues (fibroids) and I work with kids so I do get sick a lot, I’m hoping that this along with the LDN may help boost my immunity!

The Dude Abides said...


Along those lines, BookWyrm's post offers some great wisdom. I wouldn't just assume you need to buy methylfolate and start taking it. And, if you do, more is not always better.

Yes, Dude - I found that out when Dr. J clinic tested me for B6 and I was high...I wasn't even supplementing B6 daily....
Of course going down that rabbit hole - caused a few sleepless nights (slight exaggeration) - as I saw that B6 toxicity mimicked my nerve symptoms.....

---

Moderator, Lyme Forum
Symp started April/2013; Buhner's Lyme May 15-July24/14; Igenex pos. July 3/14
Doxy: July 4-Aug.24/14;Zithro July26-Aug24/14; Amox + Proben. Aug. 29/14;
added biaxin Sept. 26/14
Disc. amox,added Ceftin Nov. 20th.;
Disc. biaxin added Buhner bart herbs Dec/14;Jan/15 pulsing Tinda (w/ Ceftin);
Abx/herb break Apr-July/15; July-mino; Aug. added Rif;
Nov./15 mino - to biaxi

Regarding SpectraCell, the following is worth considering:

Testing For Micronutrients
https://youtu.be/fzdyjvabor0?t=10m58s

I e-mailed SpectraCell about this - twice - and they did not respond to either inquiry.

The entire video is worth watching. The part about micronutrient testing is only about nine minutes long at starts at 5m 11s into the video. https://youtu.be/fzdyjvabor0?t=5m11s

This is not to say don't get tested. Rather, it's about being a more informed consumer.

Hello, I also have a double mutation of this gene as well. I have been trying to get as much information about this problem as possible, can anyone help me understand what this person was saying on another message board.
"I have been researching about Methylation which is a big component of our health and has a big bearing on our immune system which involves autoimmune disease and inflammation. Often the very things we want LDN for too. Its all about how and if your body detoxs properly through your liver. You can under methylate, over methylate or be ok. If you under methylate you have low neurotransmitters seretonin and dopamine which causes depressive and pain conditions and taking anti depressants, which work well for under methylators, because they raise seretonin which helps fix the depression and pain. If you are an over methylator you have high levels of seretonin and dopamine neurotransmitters so giving you antidepressants raises them even more which can make you more depressed and suicidal. So knowing your methylator status can be key to what treatment is right for you in this and many other health conditions".
Would someone like me who has this mutation be considered as having an under methylate problem? Also I just started taking LDN, do you think this will help me with me? I read that LDN raises endorphins which causes seretonin to become lower,ins there anyway to raise seretonin naturally?

Post Edited (CalmLittleBuddha) : 12/22/2018 4:33:13 PM (GMT-7)

["raise seretonin naturally?”]

Yes, 5-htp. Its cheap, helpful in low light winter months too.

5 Science-Based Benefits of 5-HTP (Plus Dosage and Side Effects)
https://www.healthline.com/nutrition/5-htp-benefits

May 21, 2018 - Serotonin-producing 5-HTP supplements have become increasingly popular for their variety of health benefits. Here are 5 potential benefits of ...

To answer a few questions I saw in this thread--i personally will always have to take meds for this. However, because I found those multivitamin with methlyfolate I alternate between the multivitamin and the pill every other day. You can order the pills online, however they have chewable tablets at weaker strengths at my local health food/vitamin store. I started with those and slowly added more until I could handle the strength my doctor recommended. My obgyn and llmd worked together to set the dosage I needed. I word of warning when starting this treatment. Like several other meds you need to slowly increase the dose to see what works. At first your body is super excited because it is finally getting the stuff it needs and you feel beyond amazing. But some people hit a wall a few weeks in and your body freaks out a little because it's not used to having what it needs, so you take a few day break and slowly start taking it again. Your doctor should go over this with you when you discuss dosage. On the other hand just because I take meds doesn't mean you will. I got a copy from both parents and yet neither of my parents have to take meds. If your still not sure I recommend testing your homocysteine and vitamin levels.