I did some googling on nigella sativa. Seems this is one plant medicine that has been extensively studied.
I am not good at science or math, so asking for help interpreting this data for modern application.
This is the article I am talking about
Here’s what sounds like conflicting information:
(From Section 5.2)“Methanolic extracts of N. sativa have the strongest antifungal effect followed by the chloroform extracts against different strains of Candida albicans. Aqueous extracts showed no antifungal activity.”
. . . . then later in the same paragraph: “Khan et al. in 2003 reported that the aqueous extract of N. sativa seeds exhibits inhibitory effect against candidiasis in mice. A 5-fold decrease in Candida in kidneys, 8-fold in liver and 11-fold in spleen was observed in the groups of animals post-treated with the plant extract. These findings were also confirmed by Histopathological examination of the respective organs.”
The above sounds like water based extracts showed no antifungal activity. Then they said a water extract inhibited effects
against candidiasis. Does this mean the water extract did not kill or inhibit the existence of Candida, but it did inhibit negative effects normally caused by Candida,
Says methanolic extracts were the best antifungals followed by chloroform extracts. How do I find nigella sativa extracted in these methods?
Also appears to be significant differences in medicinal properties based on where the nigella comes from.
(From Section 5.1)
In regarding inhibition of S. aureus: “The inhibition obtained was higher with N. sativa ground seeds from Hadramout than with N. sativa ground seeds from Ethiopia.“
A****ng Herbs premiun black seed oil bottle says “contains .95 - 2.6 % Thymoquinone.” It it cold pressed - no alcohol or hexane. Here’s the label: https://www.amazon.com/amazing-herbs-cold-pressed-black-seed/dp/b0009j69i4/ref=mp_s_a_1_3?keywords=amazing+herbs+black+seed+oil+organic+cold+pressed&qid=1568034481&s=gateway&sprefix=amazing+herbs+&sr=8-3
The Blessed Seed Strong oil is also cold pressed. Their claims of potency are a little tricky, so you have to do math to compare. States: The Blessed Seed Strong contains 3.5%-4.6% of volatile oil of which 66% is thymoquinone. So, 66% of 3.5 - 4.6 equals 2.31 - 3.036 % thymoquinone.
Ziyad is the brand of seeds I bought.
I didn’t see the country of origin identified in the photos of any of the products.
This is my very long-winded way of wondering how to use the data in this study to find a nigella product to take that will be effective against Candida and other fungi (and hopefully other gut pathogens) and how much of any one product is required to achieve success.
Does any have herbal books that give dosages of seeds or oil for particular applications? It’s impossible to find anything on google.