Anyone tried this stuff?
Been looking into adaptogens, neurotransmitter levels, cortisol/adrenal pathways as well. Really just want to get my cortisol regulated and my anxiety down, and repair my screwed up dopamine receptors.
Was looking into ways to improve D2 receptor sensitivity. Seems like the best approach is to just limit things that are too stimulating. No sugar, not too much coffee, stay off your phone. Most supplements I read about
tend to repair dopamine receptors cause unwanted side effects. Citicholine, for example, seems to cause paradoxical anxiety, which I'm very sensitive to. Uridine is an interesting supplement, but may have some side effects if you dont get the dosage right, and its unclear what the long term effects are.
High doses of Inositol (10-14g/day) are shown to rebuild D2 receptors and improve anxiety and depression. It seems very safe, with little downside except upset stomach in some people, I want to try this one, it seems like a great supplement that people really get results with, except that it is broken down into a sugar alcohol, which I dont wnat to use while in ketosis and on this diet. I'd be very curious if anyone has tried this in a high dose.
Have started lions mane, not sure if its helping, but its a slow burner and I feel like potentially beneficial in the long run in subtle, yet important, ways. Tried theanine, does absolutely nothing, dont understand the hype around this one. I have an ashwaganda/holy basil/rhodeola adaptogen mix here that is on my list of things to try, but I've heard mixed reviews about
using this stuff long term, and herbs almost always flare me.
I have played extensively w/ B-vitamins. They always cause anxiety/wired feeling. Methylfolate drives me nuts. Phosphyditylcholine, which althoug not a b vitamin, increases methylation through conservation of SAMe, also causes anxiety. P5P, which increases dopamine activity, caused a wired feeling like i could not shut off. Also insomnia. I've found that my mehtylcycle is just too sensitive to play with directly. This often happens when the toxin load is high.
But one thing that I have
found benefit from recently is phosphaditylserine. I bought jarrow ps-100. I actually cut the liquid gel cap
open and use about
25% of it each night. The full pill was a bit much and left me feeling groggy with a headache in the am, although that improved after a few uses. But still, I'm finding i respond best to about
25%, like a PS-25. It really makes me tired if i take it around 8:30, like I cant wait to sleep, and I stay asleep throughout the night. When I only use 25% I wake up feeling relaxed, like I slept well.
Kind of rambling stream of consciousness about
the things I'm looking at, but just figured I'd pass that along.
Post Edited (dcd2103) : 8/10/2021 7:14:16 AM (GMT-6)