5 months ago I started to develop very strange and intense tendon and muscle pain. It was mostly the tendons in my forearms and calves, in addition to the muscles in my back. At times it reached a 10/10 pain.
I had had similar muscle pain while on IVIG as a result of serum sickness. I assumed it was from that. Then it happened about
3m ago when I was off IVIG. Baffled me. I initially thought I developed fibromyalgia, as the IVIG had aggravated my muscles so much that my brain began focusing on them.
I then noticed that in my notes that I had had this problem going back at least a year, just at lower levels. "Tudca causes muscle pain?" I wrote once. "Took allithiamine, muscle pain that night" I wrote another time. I wasn't sure if it was from supplements, and it seemed to be happening with so many different ones, that I just stopped them all unsure.
It wasn't until I recently started taking Life Extension benfothiamine last week and the pain came back and exploded that I dug deeper. I took 3 supplements that I knew had triggered it, and 2 that I knew definitely did not, and compared the ingredients. I crossed off the ingredients from the YES list that were also on the NO list. Some of them are a bit hard to compare, like cellulose vs microcrystalline cellulose, or stearic acid vs magnesium stearate vs vegetable stearate, but there was enough items listed that I was able to cross everything off but dicalcium phosphate, which appeared in all 3 in the YES column.
Apparently calcium phosphate can deposit in the tendons in a disease called acute calcific periarthritis, and some similar diseases. Not sure if this is definitely what did it, as this disease often attacks 1 or two tendons/muscles, and I had multiple going at once, but I feel like that's what it was. If it wasn't that, its some other filler or excipient in one of the supplements.
Point being, supplements are un-regulated and I think people with immune systems like ours have to be cognizant of the possibility that they can do more harm than good.
I found this article on some potential allergens in supplements helpful. Ironically I think she mentions dicalcium phosphate as being one of the better tolerated ones.https://actualcures.com/nutritional-supplement-ingredients-not-hypoallergenic-filler.html
Post Edited (dcd2103) : 10/12/2021 12:15:28 PM (GMT-6)