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New Member

Date Joined Mar 2008
Total Posts : 1
   Posted 3/20/2008 8:19 AM (GMT -6)   
Hi, I am new to this forum but have been getting headaches and migraines for last 14 years. Have been on sanomigran/Pizotifen for last month and already put on loads of weight. Additionally I'm really tired, keep losing words when trying to put a sentence together and lastly and most importantly am irritable as hell. So far doesn't seem to be preventing my headaches either. Don't mind these side-effects if the tables eventually start to work but just wondered if anyone else has been on these and if side effects started to wear off after a while (especially weight gain and irritability)?

Veteran Member

Date Joined Jan 2006
Total Posts : 1308
   Posted 3/20/2008 8:38 AM (GMT -6)   
Welcome to Healing Well. Sorry to hear you are having troubles with this drug. I can only offer my own personal experience with this. I put a load of weight on with this drug a very long time ago and have found difficulty shifting the weight completely even though it is a long time since I have been on it.

If you are not getting any benefit from this with your headaches, I think you need to go back and talk to your Doc about something else as this does not seem to suit you. Everyone responds in a different way to things so it is a bit of trial and error! Hang in there!

take care

Co-Moderator of the Migraine/Headache Forum

salsa chic
New Member

Date Joined Jun 2008
Total Posts : 1
   Posted 6/22/2008 8:10 AM (GMT -6)   
Hi. I was prescribed this many years ago, to prevent migraine attacks rather than try to stop them when started, as none of the usual meds seemed to do this. Can't honestly remember what effect it had on the migraines, but it did make me put on 2 stone in 6 months & I went back to GP thinking something was very wrong. Saw a different GP whose comment was, 'well, you're taking sanomigran, so what do you expect?' Great. Stopped taking it immediately & lost 1 stone, but took years & many diets, not to mention depression caused by the weight gain, before the rest moved. Am now highly susceptible to weight gain if I even look at certain foods, whereas before, I was fine. Seems this drug messes with metabolism/insulin resistance or similar. Interestingly enough, I researched on the web for the 1st time today, only to find it is used for weight gain in 3rd world countries!
My advice would be to steer well clear of sanomigran & go back to your GP ASAP. I finally ended up going to a private doctor who prescribed 'migramax', an aspirin based powder to be mixed with water & swallowed. He explained this is more effective than tablets due to the stomach 'shutting down' during migraine. Works for me, as long as I don't think too long 'am I getting an attack or not?' (This is the only medication I take & sometimes I try to resist taking it but then regret it when in full migraine mode!) If you cannot take aspirin, a paracetamol version called 'paramax' is available. Stand your ground though as I'm not sure how costly it is - when changing surgeries after moving house, they always try to change me to something else or prescribe only a small number of sachets. Good luck!
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