Long story short - Topomax worked great for me but then I got kidney stones. Neuro tried Inderal next but terrible terrible fatigue and whopper migraines. Now on amitriptyline and with the reputation of weight gain, I cut calories and started walking 2 miles a day when I started this medicine. I am taking 30 mg at bedtime and just got up to that dosage 4 days ago but I have gained a couple of pounds despite cutting calories and exercising. I saw my neuro yesterday and he said it is combo of coming off the Topomax which helps with weight and going on the elavil which may cause weight gain. He said he hated to see me go back on the Topomas because it potentially could ruin my kidneys. I didn't know that having kidney stones ultimately meant the need for a kidney transplant. Yes he said kidney transplant. But he said the decision is mine in the end as long as I knew the risks. I am trying the elavil for a while longer. Any suggestions?