I've been going through the worst migraines for the past 3 years, I have been past from doctor to doctor because nothing works on my migraines,I've had MRI's, EEG's, test, after test after test, I've been on Trimethobenzamide, nadoolol, Keppra,Depakote, Lyrica, Propranolol, Nortriptyline, Topamax, blood pressure meds like Verapamil etc, I'm now on 1200mg of Neurontin daily, and Vivactil daily, I've gone with rescue meds like maxalt, Imitrex, Fioricet, Codeine, Hydrocodone,stadole, hydroxyzine, prochlorperazine, ketoprofen with metoclopramide, a muscle relaxer called carisoprodol, and I take Ambien CR just to sleep. With all these meds not working on my migraines, would anyone consider recommending TREXIMET? I get sever migraines about 4-5 times a week, if anyone is like this and has tried the new Treximet and it worked I would love to hear from them! My thoughts are it can't hurt to try, but are the side effect really bad, thats what I worry about. I've had some really BAD reaction to some of the meds the doctors have recommended, Topamax was bad, Imitrex,Zomig, and Migranal all tightened my chest and it hurt really bad. I've even tried the Dihydroergotamine shots in my thighs which left me limping for atleast one day because it hurt so bad. Keppra and Depakote gave me nightmares of my past, like I was there all over again, so detailed. Scarey! If anyone recommends this med I would love to read some feedback. Thank you.