(taken from http://www.wellnessletter.com/html/ds/dsSAMe.php)
Not an herb, hormone, vitamin, or any other kind of nutrient, SAM-e (S-adenosylmethionine) is a synthetic form of a chemical produced naturally in the body. SAM-e is essential to a many chemical processes, including maintaining cells, manufacturing substances used by the nerves, and influencing emotions and moods.
Claims, purported benefits: "Natural" treatment for depression, arthritis, and liver disease. Said to be as effective as aspirin for pain relief, without the side effects. In Europe, on evidence that would be considered inadequate here, SAM-e is sold as a prescription drug for depression, arthritis, and liver disease. In the U.S. and Canada, SAM-e is unregulated.