Hi there, Im sorry that the amitriptaline is not working for you. I went on it 10 years ago for migraine . I am not sure if it really helped. While on it I craved food constantly especially sugar and gained a stone. I hated it. I also felt tired all the time which was depressing. Reciently I was told I would need to go back on it for neuralgia type tingling in my ear (wierd I know). Apparently it dampens down excitable nerve endings. I was not keen, instead I am on nortriptaline which is a similar anti depressent which seams to have less side effects. It is possible that this is also described for migraine. I have no experience with Topomax which seems to be mentioned a lot on these sites. I have spent some time on another antidepressent Fluox (or prozac) and although not I was not given it for migraine I suffered no migraines while on it (abiut 18 months) but did have one 2mths after coming off it so it is possible that it was working for migraine as well as menstrual depression. This antidepressent although not perfect (non of them are). Did not cause weight gain or sugar cravings which was great for me as Im a sugar addict. I would be maybe giving the amitriptalinge three more weeks but I feel there is better preventers out there.