I've had memory loss and am taking Aricept which has been helpful. I've had a bleeding stomach lining since starting Topamax and am now taking Carafate and that stopped it. Now, I've started getting bladder infections. I'm in my 40s. The doctor says I might have to take an antibiotic before sex. I assure you, all of these things are new. The last time I had a bladder infection prior to Topamax was about twenty years ago. I'm seriously frustrated. Topamax has been VERY helpful for my migraines, otherwise I would toss it out the window...except I'm sure it would kill all the birds. I'm starting to reduce my Topamax dosage, add coq10 (natural) and Verapamil. I'm also drinking more water. I'm doing my best to reduce the Topamax to the lowest possible dosage possible. I would like to get off of it, but I don't think I can psycholgoically return to daily migraines. I just know I MUST lower this drug to the barest minimum or else I could fall apart. PLEASE, when taking this med, keep your dosages tiny and be careful for s/e's. Also, check out the Physician's Desk Reference (PDR) available on-line for side effects. The list of common and uncommon ones is very long. They include many memory issues, depression, anxiety, urinary tract infections, kidney stones, acne, indegestion, sexual issues and all sorts of things. What we will put up with to get rid of these darn migraines. Hang in there and be careful!